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Cell Signal Transduction Research Antibodies
CD158z Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight44928Da
Protein NameKiller cell immunoglobulin-like receptor 3DL3
Human Gene Id100133046
Human Swiss Prot NoQ8N743
SpecificityCD158z Polyclonal Antibody detects endogenous levels of CD158z protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameKIR3DL3; CD158Z; KIR3DL7; KIRC1; Killer cell immunoglobulin-like receptor 3DL3; CD158 antigen-like family member Z; Killer cell inhibitory receptor 1; CD158z
Observed Band(KD)45
Functionfunction:Receptor on natural killer cells. May inhibit the activity of NK cells thus preventing cell lysis.,similarity:Belongs to the immunoglobulin superfamily.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,
Subcellular LocationCell membrane; Single-pass type I membrane protein.
ExpressionPeripheral blood,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human KIR3DL3. AA range:231-280
Gene NameKIR3DL3
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Backgroundkiller cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3(KIR3DL3) Homo sapiens Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the
Conjugated Antibody
This product is also available conjugated. Format: E20-75273-Conjugate. Price: $485 / Size: 100μl.
E20-75273-FITC$485 / 100μlE20-75273-Biotin$485 / 100μlE20-75273-HRP$485 / 100μlE20-75273-AP$485 / 100μlE20-75273-AF350$485 / 100μlE20-75273-AF405M$485 / 100μlE20-75273-AF488$485 / 100μlE20-75273-AF514$485 / 100μlE20-75273-AF532$485 / 100μlE20-75273-AF555$485 / 100μlE20-75273-AF568$485 / 100μlE20-75273-AF405S$485 / 100μlE20-75273-AF405L$485 / 100μlE20-75273-AF546$485 / 100μlE20-75273-AF594$485 / 100μlE20-75273-AF610$485 / 100μlE20-75273-AF635$485 / 100μlE20-75273-AF647$485 / 100μlE20-75273-AF680$485 / 100μlE20-75273-AF700$485 / 100μlE20-75273-AF750$485 / 100μlE20-75273-AF790$485 / 100μlE20-75273-APC$485 / 100μlE20-75273-PE$485 / 100μlE20-75273-Cy3$485 / 100μlE20-75273-Cy5$485 / 100μlE20-75273-Cy5.5$485 / 100μlE20-75273-Cy7$485 / 100μlE20-75273-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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