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Cell Signal Transduction Research Antibodies
CD307 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight106437Da
Protein NameFc receptor-like protein 5
Human Gene Id83416
Human Swiss Prot NoQ96RD9
Mouse Swiss Prot NoQ68SN8
SpecificityCD307 Polyclonal Antibody detects endogenous levels of CD307 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameFCRL5; FCRH5; IRTA2; Fc receptor-like protein 5; FcR-like protein 5; FcRL5; BXMAS1; Fc receptor homolog 5; FcRH5; Immune receptor translocation-associated protein 2; CD307e
Observed Band(KD)110
Functiondisease:A chromosomal aberration involving FCRL5 is found in Burkitt lymphoma (BL) cell lines with 1q21 abnormalities [MIM:113970]. Duplication dup(1)(q21q32).,domain:Contains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM).,function:May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells.,similarity:Contains 8 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Expressed in marginal zone B-cells, immunoblasts, tonsillar germinal center centrocytes and in the intraepithelial and interfollicular regions of the tonsil. Expressed in many lymphoma cell lines and on hairy cell leukemia cells. Isoform 1, isoform 3, isoform 4 and isoform 5 are detected in lymph node, spleen, bone marro
Subcellular LocationCell membrane ; Single-pass type I membrane protein .
ExpressionExpressed in marginal zone B-cells, immunoblasts, tonsillar germinal center centrocytes and in the intraepithelial and interfollicular regions of the tonsil. Expressed in many lymphoma cell lines and on hairy cell leukemia cells. Isoform 1, isoform 3, isoform 4 and isoform 5 are detected in lymph node, spleen, bone marrow, and small intestine with preponderance of isoform 3. Expressed in mature and memory B-cells and down-regulated in germinal center cells (at protein level).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human FCRL5. AA range:191-240
Gene NameFCRL5
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
BackgroundFc receptor like 5(FCRL5) Homo sapiens This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010],
Conjugated Antibody
This product is also available conjugated. Format: E20-75268-Conjugate. Price: $485 / Size: 100μl.
E20-75268-FITC$485 / 100μlE20-75268-Biotin$485 / 100μlE20-75268-HRP$485 / 100μlE20-75268-AP$485 / 100μlE20-75268-AF350$485 / 100μlE20-75268-AF405M$485 / 100μlE20-75268-AF488$485 / 100μlE20-75268-AF514$485 / 100μlE20-75268-AF532$485 / 100μlE20-75268-AF555$485 / 100μlE20-75268-AF568$485 / 100μlE20-75268-AF405S$485 / 100μlE20-75268-AF405L$485 / 100μlE20-75268-AF546$485 / 100μlE20-75268-AF594$485 / 100μlE20-75268-AF610$485 / 100μlE20-75268-AF635$485 / 100μlE20-75268-AF647$485 / 100μlE20-75268-AF680$485 / 100μlE20-75268-AF700$485 / 100μlE20-75268-AF750$485 / 100μlE20-75268-AF790$485 / 100μlE20-75268-APC$485 / 100μlE20-75268-PE$485 / 100μlE20-75268-Cy3$485 / 100μlE20-75268-Cy5$485 / 100μlE20-75268-Cy5.5$485 / 100μlE20-75268-Cy7$485 / 100μlE20-75268-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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