World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
IGF-IIR Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight80859Da
Protein NameEndosialin
Human Gene Id57124
Human Swiss Prot NoQ9HCU0
Mouse Swiss Prot NoQ91V98
SpecificityCD248 Polyclonal Antibody detects endogenous levels of CD248 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCD248; CD164L1; TEM1; Endosialin; Tumor endothelial marker 1; CD248
Observed Band(KD)80
Functionfunction:May play a role in tumor angiogenesis.,online information:Endosialin,PTM:May be N-glycosylated.,PTM:O-glycosylated with sialylated oligosaccharides.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 Sushi (CCP/SCR) domain.,tissue specificity:Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.,
Subcellular LocationMembrane ; Single-pass type I membrane protein .
ExpressionExpressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CD248. AA range:341-390
Gene NameCD248
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundfunction:May play a role in tumor angiogenesis.,online information:Endosialin,PTM:May be N-glycosylated.,PTM:O-glycosylated with sialylated oligosaccharides.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 Sushi (CCP/SCR) domain.,tissue specificity:Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.,
Conjugated Antibody
This product is also available conjugated. Format: E20-75267-Conjugate. Price: $485 / Size: 100μl.
E20-75267-FITC$485 / 100μlE20-75267-Biotin$485 / 100μlE20-75267-HRP$485 / 100μlE20-75267-AP$485 / 100μlE20-75267-AF350$485 / 100μlE20-75267-AF405M$485 / 100μlE20-75267-AF488$485 / 100μlE20-75267-AF514$485 / 100μlE20-75267-AF532$485 / 100μlE20-75267-AF555$485 / 100μlE20-75267-AF568$485 / 100μlE20-75267-AF405S$485 / 100μlE20-75267-AF405L$485 / 100μlE20-75267-AF546$485 / 100μlE20-75267-AF594$485 / 100μlE20-75267-AF610$485 / 100μlE20-75267-AF635$485 / 100μlE20-75267-AF647$485 / 100μlE20-75267-AF680$485 / 100μlE20-75267-AF700$485 / 100μlE20-75267-AF750$485 / 100μlE20-75267-AF790$485 / 100μlE20-75267-APC$485 / 100μlE20-75267-PE$485 / 100μlE20-75267-Cy3$485 / 100μlE20-75267-Cy5$485 / 100μlE20-75267-Cy5.5$485 / 100μlE20-75267-Cy7$485 / 100μlE20-75267-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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