World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
IL-2Rβ Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight61117Da
Protein NameInterleukin-2 receptor subunit beta
Human Gene Id3560
Human Swiss Prot NoP14784
Mouse Swiss Prot NoP16297
SpecificityIL-2Rβ Polyclonal Antibody detects endogenous levels of IL-2Rβ protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameIL2RB; Interleukin-2 receptor subunit beta; IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB; High affinity IL-2 receptor subunit beta; p70-75; p75; CD122
Observed Band(KD)61
Functiondomain:The box 1 motif is required for JAK interaction and/or activation.,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.,function:Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.,similarity:Belongs to the type I cytokine receptor family. Type 4 subfamily.,similarity:Contains 1 fibronectin type-III domain.,subunit:Non-covalent dimer of an alpha and a beta chains. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta chain), and a low affinity monomer (alpha chain). The high and intermediate affinity forms also associate with a gamma chain. Interacts with SHB upon interleukin stimulation. Interacts with HTLV-1 accessory protein p12I.,
Subcellular LocationCell membrane ; Single-pass type I membrane protein .
ExpressionLung,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the N-terminal region of human IL2RB. AA range:31-80
Gene NameIL2RB
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundinterleukin 2 receptor subunit beta(IL2RB) Homo sapiens The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an up
Conjugated Antibody
This product is also available conjugated. Format: E20-75264-Conjugate. Price: $485 / Size: 100μl.
E20-75264-FITC$485 / 100μlE20-75264-Biotin$485 / 100μlE20-75264-HRP$485 / 100μlE20-75264-AP$485 / 100μlE20-75264-AF350$485 / 100μlE20-75264-AF405M$485 / 100μlE20-75264-AF488$485 / 100μlE20-75264-AF514$485 / 100μlE20-75264-AF532$485 / 100μlE20-75264-AF555$485 / 100μlE20-75264-AF568$485 / 100μlE20-75264-AF405S$485 / 100μlE20-75264-AF405L$485 / 100μlE20-75264-AF546$485 / 100μlE20-75264-AF594$485 / 100μlE20-75264-AF610$485 / 100μlE20-75264-AF635$485 / 100μlE20-75264-AF647$485 / 100μlE20-75264-AF680$485 / 100μlE20-75264-AF700$485 / 100μlE20-75264-AF750$485 / 100μlE20-75264-AF790$485 / 100μlE20-75264-APC$485 / 100μlE20-75264-PE$485 / 100μlE20-75264-Cy3$485 / 100μlE20-75264-Cy5$485 / 100μlE20-75264-Cy5.5$485 / 100μlE20-75264-Cy7$485 / 100μlE20-75264-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits