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Cell Signal Transduction Research Antibodies
IL-1RI Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight65402Da
Protein NameInterleukin-1 receptor type 1
Human Gene Id3554
Human Swiss Prot NoP14778
Mouse Swiss Prot NoP13504
SpecificityIL-1RI Polyclonal Antibody detects endogenous levels of IL-1RI protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameIL1R1; IL1R; IL1RA; IL1RT1; Interleukin-1 receptor type 1; IL-1R-1; IL-1RT-1; IL-1RT1; CD121 antigen-like family member A; Interleukin-1 receptor alpha; IL-1R-alpha; Interleukin-1 receptor type I; p80; CD121a
Observed Band(KD)75
Functionfunction:Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.,similarity:Belongs to the interleukin-1 receptor family.,similarity:Contains 1 TIR domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Binds IL1RAP.,
Subcellular LocationMembrane ; Single-pass type I membrane protein . Cell membrane . Secreted .
ExpressionExpressed in T-helper cell subsets. Preferentially expressed in T-helper 1 (Th1) cells.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the N-terminal region of human IL1R1. AA range:31-80
Gene NameIL1R1
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Backgroundinterleukin 1 receptor type 1(IL1R1) Homo sapiens This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013],
Conjugated Antibody
This product is also available conjugated. Format: E20-75263-Conjugate. Price: $485 / Size: 100μl.
E20-75263-FITC$485 / 100μlE20-75263-Biotin$485 / 100μlE20-75263-HRP$485 / 100μlE20-75263-AP$485 / 100μlE20-75263-AF350$485 / 100μlE20-75263-AF405M$485 / 100μlE20-75263-AF488$485 / 100μlE20-75263-AF514$485 / 100μlE20-75263-AF532$485 / 100μlE20-75263-AF555$485 / 100μlE20-75263-AF568$485 / 100μlE20-75263-AF405S$485 / 100μlE20-75263-AF405L$485 / 100μlE20-75263-AF546$485 / 100μlE20-75263-AF594$485 / 100μlE20-75263-AF610$485 / 100μlE20-75263-AF635$485 / 100μlE20-75263-AF647$485 / 100μlE20-75263-AF680$485 / 100μlE20-75263-AF700$485 / 100μlE20-75263-AF750$485 / 100μlE20-75263-AF790$485 / 100μlE20-75263-APC$485 / 100μlE20-75263-PE$485 / 100μlE20-75263-Cy3$485 / 100μlE20-75263-Cy5$485 / 100μlE20-75263-Cy5.5$485 / 100μlE20-75263-Cy7$485 / 100μlE20-75263-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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