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Cell Signal Transduction Research Antibodies
CD116 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight46207Da
Protein NameGranulocyte-macrophage colony-stimulating factor receptor subunit alpha
Human Gene Id1438
Human Swiss Prot NoP15509
Mouse Swiss Prot NoQ00941
SpecificityCD116 Polyclonal Antibody detects endogenous levels of CD116 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCSF2RA; CSF2R; CSF2RY; Granulocyte-macrophage colony-stimulating factor receptor subunit alpha; GM-CSF-R-alpha; GMCSFR-alpha; GMR-alpha; CDw116; CD116
Observed Band(KD)44
Functiondomain:The box 1 motif is required for JAK interaction and/or activation.,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.,function:Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,similarity:Belongs to the type I cytokine receptor family. Type 5 subfamily.,subunit:Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors.,
Subcellular LocationCell membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted .; [Isoform 4]: Secreted .; [Isoform 6]: Secreted .
ExpressionBlood,Placenta,Synovial membrane tissue,Uterus,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CSF2RA. AA range:121-170
Gene NameCSF2RA
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Backgroundcolony stimulating factor 2 receptor alpha subunit(CSF2RA) Homo sapiens The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75262-Conjugate. Price: $485 / Size: 100μl.
E20-75262-FITC$485 / 100μlE20-75262-Biotin$485 / 100μlE20-75262-HRP$485 / 100μlE20-75262-AP$485 / 100μlE20-75262-AF350$485 / 100μlE20-75262-AF405M$485 / 100μlE20-75262-AF488$485 / 100μlE20-75262-AF514$485 / 100μlE20-75262-AF532$485 / 100μlE20-75262-AF555$485 / 100μlE20-75262-AF568$485 / 100μlE20-75262-AF405S$485 / 100μlE20-75262-AF405L$485 / 100μlE20-75262-AF546$485 / 100μlE20-75262-AF594$485 / 100μlE20-75262-AF610$485 / 100μlE20-75262-AF635$485 / 100μlE20-75262-AF647$485 / 100μlE20-75262-AF680$485 / 100μlE20-75262-AF700$485 / 100μlE20-75262-AF750$485 / 100μlE20-75262-AF790$485 / 100μlE20-75262-APC$485 / 100μlE20-75262-PE$485 / 100μlE20-75262-Cy3$485 / 100μlE20-75262-Cy5$485 / 100μlE20-75262-Cy5.5$485 / 100μlE20-75262-Cy7$485 / 100μlE20-75262-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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