Product Information
Molecular Weight55165Da
Protein NameLeukocyte immunoglobulin-like receptor subfamily A member 4
Human Gene Id23547
Human Swiss Prot NoP59901
SpecificityCD85g Polyclonal Antibody detects endogenous levels of CD85g protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameLILRA4; ILT7; Leukocyte immunoglobulin-like receptor subfamily A member 4; CD85 antigen-like family member G; Immunoglobulin-like transcript 7; ILT-7; CD85g
Observed Band(KD)55
Functionfunction:May act as receptor for class I MHC antigens. Ligand binding leads to the activation of eosinophils and to the release of RNASE2, IL4 and leukotriene C4.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Detected on eosinophils, neutrophils and monocytes.,
Subcellular LocationCell membrane ; Single-pass type I membrane protein .
ExpressionDetected on plasmacytoid dendritic cells (at protein level). Detected on plasmacytoid dendritic cells, but not on monocytes or B cells.
Backgroundleukocyte immunoglobulin like receptor A4(LILRA4) Homo sapiens This gene encodes an immunoglobulin-like cell surface protein that is expressed predominantly on plasmacytoid dendritic cells (PDCs) and modulates the function of these cells in the immune response. Expression of this gene is downregulated by interleukin 3 (IL3). This gene is one of a cluster of highly related genes located at chromosomal region 19q13.4. [provided by RefSeq, Jan 2015],