Product Information
Molecular Weight63368Da
Protein Name5'-nucleotidase
Human Gene Id4907
Human Swiss Prot NoP21589
Mouse Swiss Prot NoQ61503
SpecificityCD73 Polyclonal Antibody detects endogenous levels of CD73 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameNT5E; NT5; NTE; 5'-nucleotidase; 5'-NT; Ecto-5'-nucleotidase; CD73
Observed Band(KD)68
Functioncatalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Zinc.,disease:There is a decrease in the activity of NT5 in B-cell chronic lymphocytic leukemia.,function:Hydrolyzes extracellular nucleotides into membrane permeable nucleosides.,similarity:Belongs to the 5'-nucleotidase family.,subunit:Homodimer; disulfide-linked.,
Subcellular LocationCell membrane ; Lipid-anchor, GPI-anchor .
ExpressionLeukocyte,Liver,Placenta,Skin,
Background5'-nucleotidase ecto(NT5E) Homo sapiens The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011],