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Cell Signal Transduction Research Antibodies
CD55 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight41400Da
Protein NameComplement decay-accelerating factor
Human Gene Id1604
Human Swiss Prot NoP08174
SpecificityCD55 Polyclonal Antibody detects endogenous levels of CD55 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCD55; CR; DAF; Complement decay-accelerating factor; CD55
Observed Band(KD)42
Functiondomain:The first Sushi domain (SCR1) is not necessary for function. SCR2 and SCR4 provide the proper conformation for the active site on SCR3.,function:This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.,online information:Blood group antigen gene mutation database,online information:CD55 mutation db,online information:Decay-accelerating factor entry,online information:Icosahedral capsid structure,polymorphism:Responsible for the Cromer blood group system. It consists of at least
Subcellular Location[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform 3]: Secreted .; [Isoform 4]: Secreted .; [Isoform 5]: Secreted .; [Isoform 6]: Cell membrane ; Lipid-anchor, GPI-anchor .; [Isoform 7]: Cell membrane ; Lipid-anchor, GPI-anchor .
ExpressionExpressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CD55. AA range:241-290
Gene NameCD55
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
BackgroundCD55 molecule (Cromer blood group)(CD55) Homo sapiens This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins. [provided by RefSeq, Jul 2014],
Conjugated Antibody
This product is also available conjugated. Format: E20-75250-Conjugate. Price: $485 / Size: 100μl.
E20-75250-FITC$485 / 100μlE20-75250-Biotin$485 / 100μlE20-75250-HRP$485 / 100μlE20-75250-AP$485 / 100μlE20-75250-AF350$485 / 100μlE20-75250-AF405M$485 / 100μlE20-75250-AF488$485 / 100μlE20-75250-AF514$485 / 100μlE20-75250-AF532$485 / 100μlE20-75250-AF555$485 / 100μlE20-75250-AF568$485 / 100μlE20-75250-AF405S$485 / 100μlE20-75250-AF405L$485 / 100μlE20-75250-AF546$485 / 100μlE20-75250-AF594$485 / 100μlE20-75250-AF610$485 / 100μlE20-75250-AF635$485 / 100μlE20-75250-AF647$485 / 100μlE20-75250-AF680$485 / 100μlE20-75250-AF700$485 / 100μlE20-75250-AF750$485 / 100μlE20-75250-AF790$485 / 100μlE20-75250-APC$485 / 100μlE20-75250-PE$485 / 100μlE20-75250-Cy3$485 / 100μlE20-75250-Cy5$485 / 100μlE20-75250-Cy5.5$485 / 100μlE20-75250-Cy7$485 / 100μlE20-75250-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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