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Cell Signal Transduction Research Antibodies
CD50 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight59384Da
Protein NameIntercellular adhesion molecule 3
Human Gene Id3385
Human Swiss Prot NoP32942
SpecificityCD50 Polyclonal Antibody detects endogenous levels of CD50 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameICAM3; Intercellular adhesion molecule 3; ICAM-3; CDw50; ICAM-R; CD50
Observed Band(KD)42-60
Functionfunction:ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2.,online information:ICAM-3,PTM:N-glycosylated; glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains.,PTM:Upon stimulation by a physiologic stimuli becomes rapidly and transiently phosphorylated on serine residues.,similarity:Belongs to the immunoglobulin superfamily. ICAM family.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,
Subcellular LocationMembrane; Single-pass type I membrane protein.
ExpressionLeukocytes.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human ICAM3. AA range:271-320
Gene NameICAM3
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Backgroundintercellular adhesion molecule 3(ICAM3) Homo sapiens The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016],
Conjugated Antibody
This product is also available conjugated. Format: E20-75249-Conjugate. Price: $485 / Size: 100μl.
E20-75249-FITC$485 / 100μlE20-75249-Biotin$485 / 100μlE20-75249-HRP$485 / 100μlE20-75249-AP$485 / 100μlE20-75249-AF350$485 / 100μlE20-75249-AF405M$485 / 100μlE20-75249-AF488$485 / 100μlE20-75249-AF514$485 / 100μlE20-75249-AF532$485 / 100μlE20-75249-AF555$485 / 100μlE20-75249-AF568$485 / 100μlE20-75249-AF405S$485 / 100μlE20-75249-AF405L$485 / 100μlE20-75249-AF546$485 / 100μlE20-75249-AF594$485 / 100μlE20-75249-AF610$485 / 100μlE20-75249-AF635$485 / 100μlE20-75249-AF647$485 / 100μlE20-75249-AF680$485 / 100μlE20-75249-AF700$485 / 100μlE20-75249-AF750$485 / 100μlE20-75249-AF790$485 / 100μlE20-75249-APC$485 / 100μlE20-75249-PE$485 / 100μlE20-75249-Cy3$485 / 100μlE20-75249-Cy5$485 / 100μlE20-75249-Cy5.5$485 / 100μlE20-75249-Cy7$485 / 100μlE20-75249-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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