Product Information
Molecular Weight27683Da
Protein NameCD48 antigen
Human Gene Id962
Human Swiss Prot NoP09326
Mouse Swiss Prot NoP18181
SpecificityCD48 Polyclonal Antibody detects endogenous levels of CD48 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCD48; BCM1; BLAST1; CD48 antigen; B-lymphocyte activation marker BLAST-1; BCM1 surface antigen; Leukocyte antigen MEM-102; TCT.1; CD48
Observed Band(KD)40
Functionfunction:Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,
Subcellular LocationCell membrane ; Lipid-anchor, GPI-anchor . Secreted .
ExpressionWidely expressed on all hematopoietic cells.
BackgroundCD48 molecule(CD48) Homo sapiens This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],