World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
CD32-B/C Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight34044Da
Protein NameLow affinity immunoglobulin gamma Fc region receptor II-b/Low affinity immunoglobulin gamma Fc region receptor II-c
Human Gene Id2213
Human Swiss Prot NoP31994
SpecificityCD32-B/C Polyclonal Antibody detects endogenous levels of CD32-B/C protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameFCGR2B; CD32; FCG2; IGFR2; Low affinity immunoglobulin gamma Fc region receptor II-b; IgG Fc receptor II-b; CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; CD32; FCGR2C; CD32; FCG2; IGFR2;Low affinity immunoglobulin gamma Fc region receptor II-c; IgG Fc receptor II-c; CDw32; Fc-gamma RII-c; Fc-gamma-RIIc; FcRII-c; CD32
Observed Band(KD)35
Functionimmune response,
Subcellular LocationCell membrane; Single-pass type I membrane protein.
ExpressionIs the most broadly distributed Fc-gamma-receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human FCGR2B/C. AA range:141-190
Gene NameFCGR2B/FCGR2C
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
BackgroundLow affinity immunoglobulin gamma Fc region receptor II-b/Low affinity immunoglobulin gamma Fc region receptor II-c encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
Conjugated Antibody
This product is also available conjugated. Format: E20-75246-Conjugate. Price: $485 / Size: 100μl.
E20-75246-FITC$485 / 100μlE20-75246-Biotin$485 / 100μlE20-75246-HRP$485 / 100μlE20-75246-AP$485 / 100μlE20-75246-AF350$485 / 100μlE20-75246-AF405M$485 / 100μlE20-75246-AF488$485 / 100μlE20-75246-AF514$485 / 100μlE20-75246-AF532$485 / 100μlE20-75246-AF555$485 / 100μlE20-75246-AF568$485 / 100μlE20-75246-AF405S$485 / 100μlE20-75246-AF405L$485 / 100μlE20-75246-AF546$485 / 100μlE20-75246-AF594$485 / 100μlE20-75246-AF610$485 / 100μlE20-75246-AF635$485 / 100μlE20-75246-AF647$485 / 100μlE20-75246-AF680$485 / 100μlE20-75246-AF700$485 / 100μlE20-75246-AF750$485 / 100μlE20-75246-AF790$485 / 100μlE20-75246-APC$485 / 100μlE20-75246-PE$485 / 100μlE20-75246-Cy3$485 / 100μlE20-75246-Cy5$485 / 100μlE20-75246-Cy5.5$485 / 100μlE20-75246-Cy7$485 / 100μlE20-75246-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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