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Cell Signal Transduction Research Antibodies
CD28 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight30819Da
Protein NameInterleukin-2 receptor subunit alpha
Human Gene Id3559
Human Swiss Prot NoP01589
Mouse Swiss Prot NoP01590
SpecificityIL-2Rα Polyclonal Antibody detects endogenous levels of IL-2Rα protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameIL2RA; Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25
Observed Band(KD)30
Functiondisease:Genetic variations in IL2RA are associated with susceptibility to insulin-dependent diabetes mellitus type 10 (IDDM10) [MIM:601942].,function:Receptor for interleukin-2.,online information:IL2RA mutation db,similarity:Contains 2 Sushi (CCP/SCR) domains.,subunit:Non-covalent dimer of an alpha and a beta chains. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta chain), and a low affinity monomer (alpha chain). The high and intermediate affinity forms also associate with a gamma chain.,
Subcellular LocationMembrane; Single-pass type I membrane protein.
ExpressionThymus,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human IL2RA. AA range:61-110
Gene NameIL2RA
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundinterleukin 2 receptor subunit alpha(IL2RA) Homo sapiens The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009],
Conjugated Antibody
This product is also available conjugated. Format: E20-75243-Conjugate. Price: $485 / Size: 100μl.
E20-75243-FITC$485 / 100μlE20-75243-Biotin$485 / 100μlE20-75243-HRP$485 / 100μlE20-75243-AP$485 / 100μlE20-75243-AF350$485 / 100μlE20-75243-AF405M$485 / 100μlE20-75243-AF488$485 / 100μlE20-75243-AF514$485 / 100μlE20-75243-AF532$485 / 100μlE20-75243-AF555$485 / 100μlE20-75243-AF568$485 / 100μlE20-75243-AF405S$485 / 100μlE20-75243-AF405L$485 / 100μlE20-75243-AF546$485 / 100μlE20-75243-AF594$485 / 100μlE20-75243-AF610$485 / 100μlE20-75243-AF635$485 / 100μlE20-75243-AF647$485 / 100μlE20-75243-AF680$485 / 100μlE20-75243-AF700$485 / 100μlE20-75243-AF750$485 / 100μlE20-75243-AF790$485 / 100μlE20-75243-APC$485 / 100μlE20-75243-PE$485 / 100μlE20-75243-Cy3$485 / 100μlE20-75243-Cy5$485 / 100μlE20-75243-Cy5.5$485 / 100μlE20-75243-Cy7$485 / 100μlE20-75243-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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