World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
CD1E Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight35986Da
Protein NameT-cell surface glycoprotein CD1e membrane-associated
Human Gene Id913
Human Swiss Prot NoP15812
SpecificityCD1E Polyclonal Antibody detects endogenous levels of CD1E protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCD1E; T-cell surface glycoprotein CD1e, membrane-associated; hCD1e; R2G1; CD1e
Observed Band(KD)42
Functionfunction:Required for the presentation of glycolipid antigens on the cell surface.,PTM:Mono-ubiquitinated.,PTM:Proteolytically cleaved in endosomes to yield a soluble form.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,subcellular location:Predominantly localized in the trans-Golgi network in immature dendritic cells, and as a cleaved, soluble protein in the lysosome lumen of mature dendritic cells.,subunit:Heterodimer with B2M (beta-2-microglobulin).,tissue specificity:Expressed on cortical thymocytes, dendritic cells, Langerhans cells, on certain T-cell leukemias, and in various other tissues.,
Subcellular Location[T-cell surface glycoprotein CD1e, membrane-associated]: Golgi apparatus membrane; Single-pass type I membrane protein. Early endosome. Late endosome. Predominantly localized in the trans-Golgi network in immature dendritic cells, and as a cleaved, soluble protein in the lysosome lumen of mature dendritic cells.; [T-cell surface glycoprotein CD1e, soluble]: Lysosome lumen.
ExpressionExpressed on cortical thymocytes, dendritic cells, Langerhans cells, on certain T-cell leukemias, and in various other tissues.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human CD1E. AA range:321-370
Gene NameCD1E
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
BackgroundCD1e molecule(CD1E) Homo sapiens This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been desc
Conjugated Antibody
This product is also available conjugated. Format: E20-75240-Conjugate. Price: $485 / Size: 100μl.
E20-75240-FITC$485 / 100μlE20-75240-Biotin$485 / 100μlE20-75240-HRP$485 / 100μlE20-75240-AP$485 / 100μlE20-75240-AF350$485 / 100μlE20-75240-AF405M$485 / 100μlE20-75240-AF488$485 / 100μlE20-75240-AF514$485 / 100μlE20-75240-AF532$485 / 100μlE20-75240-AF555$485 / 100μlE20-75240-AF568$485 / 100μlE20-75240-AF405S$485 / 100μlE20-75240-AF405L$485 / 100μlE20-75240-AF546$485 / 100μlE20-75240-AF594$485 / 100μlE20-75240-AF610$485 / 100μlE20-75240-AF635$485 / 100μlE20-75240-AF647$485 / 100μlE20-75240-AF680$485 / 100μlE20-75240-AF700$485 / 100μlE20-75240-AF750$485 / 100μlE20-75240-AF790$485 / 100μlE20-75240-APC$485 / 100μlE20-75240-PE$485 / 100μlE20-75240-Cy3$485 / 100μlE20-75240-Cy5$485 / 100μlE20-75240-Cy5.5$485 / 100μlE20-75240-Cy7$485 / 100μlE20-75240-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits