TFPI Polyclonal Antibody

Name: TFPI Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75235
Price: 225 USD
Availability: InStock

E20-75235Cite ID: EN0055368Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight33440Da

Protein NameTissue factor pathway inhibitor

Human Gene Id7035

Human Swiss Prot NoP10646

Mouse Swiss Prot NoO54819

SpecificityTFPI Polyclonal Antibody detects endogenous levels of TFPI protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameTFPI; LACI; TFPI1; Tissue factor pathway inhibitor; TFPI; Extrinsic pathway inhibitor; EPI; Lipoprotein-associated coagulation inhibitor; LACI

Observed Band(KD)34

Functiondomain:This inhibitor contains three inhibitory domains. The first domain interacts with VIIa and TF, the second one with Xa.,function:Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.,online information:TFPI entry,PTM:O-glycosylated.,similarity:Contains 2 BPTI/Kunitz inhibitor domains.,similarity:Contains 3 BPTI/Kunitz inhibitor domains.,tissue specificity:Mostly in endothelial cells.,

Subcellular Location[Isoform Alpha]: Secreted.; [Isoform Beta]: Microsome membrane ; Lipid-anchor, GPI-anchor .

ExpressionMostly in endothelial cells.

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human TFPI. AA range:251-300

Gene NameTFPI

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Backgroundtissue factor pathway inhibitor(TFPI) Homo sapiens This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75235-Conjugate. Price: $485 / Size: 100μl.

E20-75235-FITC$485 / 100μlE20-75235-Biotin$485 / 100μlE20-75235-HRP$485 / 100μlE20-75235-AP$485 / 100μlE20-75235-AF350$485 / 100μlE20-75235-AF405M$485 / 100μlE20-75235-AF488$485 / 100μlE20-75235-AF514$485 / 100μlE20-75235-AF532$485 / 100μlE20-75235-AF555$485 / 100μlE20-75235-AF568$485 / 100μlE20-75235-AF405S$485 / 100μlE20-75235-AF405L$485 / 100μlE20-75235-AF546$485 / 100μlE20-75235-AF594$485 / 100μlE20-75235-AF610$485 / 100μlE20-75235-AF635$485 / 100μlE20-75235-AF647$485 / 100μlE20-75235-AF680$485 / 100μlE20-75235-AF700$485 / 100μlE20-75235-AF750$485 / 100μlE20-75235-AF790$485 / 100μlE20-75235-APC$485 / 100μlE20-75235-PE$485 / 100μlE20-75235-Cy3$485 / 100μlE20-75235-Cy5$485 / 100μlE20-75235-Cy5.5$485 / 100μlE20-75235-Cy7$485 / 100μlE20-75235-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.