SNAP 23 Polyclonal Antibody

Name: SNAP 23 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75231
Price: 225 USD
Availability: InStock

E20-75231Cite ID: EN0055364Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight23210Da

Protein NameSynaptosomal-associated protein 23

Human Gene Id8773

Human Swiss Prot NoO00161

Mouse Swiss Prot NoO09044

SpecificitySNAP 23 Polyclonal Antibody detects endogenous levels of SNAP 23 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameSNAP23; Synaptosomal-associated protein 23; SNAP-23; Vesicle-membrane fusion protein SNAP-23

Observed Band(KD)25

Functionfunction:Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.,similarity:Belongs to the SNAP-25 family.,similarity:Contains 2 t-SNARE coiled-coil homology domains.,subcellular location:Mainly localized to the plasma membrane.,subunit:Binds simultaneously to SNAP25BP and SYN4. Found in a complex with VAMP8 and STX4 in pancreas (By similarity). Binds tightly to multiple syntaxins and synaptobrevins/VAMPs. Found in a complex with VAMP8 and STX1A.,tissue specificity:Ubiquitous. Highest levels where found in placenta.,

Subcellular LocationCell membrane; Peripheral membrane protein. Cell membrane; Lipid-anchor. Cell junction, synapse, synaptosome. Mainly localized to the plasma membrane.

ExpressionUbiquitous. Highest levels where found in placenta.

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human SNAP23. AA range:151-200

Gene NameSNAP-23

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Backgroundsynaptosome associated protein 23(SNAP23) Homo sapiens Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the

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Conjugated Antibody

This product is also available conjugated. Format: E20-75231-Conjugate. Price: $485 / Size: 100μl.

E20-75231-FITC$485 / 100μlE20-75231-Biotin$485 / 100μlE20-75231-HRP$485 / 100μlE20-75231-AP$485 / 100μlE20-75231-AF350$485 / 100μlE20-75231-AF405M$485 / 100μlE20-75231-AF488$485 / 100μlE20-75231-AF514$485 / 100μlE20-75231-AF532$485 / 100μlE20-75231-AF555$485 / 100μlE20-75231-AF568$485 / 100μlE20-75231-AF405S$485 / 100μlE20-75231-AF405L$485 / 100μlE20-75231-AF546$485 / 100μlE20-75231-AF594$485 / 100μlE20-75231-AF610$485 / 100μlE20-75231-AF635$485 / 100μlE20-75231-AF647$485 / 100μlE20-75231-AF680$485 / 100μlE20-75231-AF700$485 / 100μlE20-75231-AF750$485 / 100μlE20-75231-AF790$485 / 100μlE20-75231-APC$485 / 100μlE20-75231-PE$485 / 100μlE20-75231-Cy3$485 / 100μlE20-75231-Cy5$485 / 100μlE20-75231-Cy5.5$485 / 100μlE20-75231-Cy7$485 / 100μlE20-75231-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.