Product Information
Molecular Weight102410Da
Protein NameNeuropilin-2
Human Gene Id8828
Human Swiss Prot NoO60462
Mouse Gene Id18187
Mouse Swiss Prot NoO35375
Rat Gene Id81527
Rat Swiss Prot NoO35276
SpecificityNeuropilin-2 Polyclonal Antibody detects endogenous levels of Neuropilin-2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameNRP2; VEGF165R2; Neuropilin-2; Vascular endothelial cell growth factor 165 receptor 2
Observed Band(KD)100
Functionfunction:High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.,similarity:Belongs to the neuropilin family.,similarity:Contains 1 MAM domain.,similarity:Contains 2 CUB domains.,similarity:Contains 2 F5/8 type C domains.,subunit:Heterodimer with NRP1 (Probable). Binds PLXNB1.,
Subcellular LocationMembrane ; Single-pass type I membrane protein .; [Isoform s9]: Secreted .
ExpressionBrain,Human endometrium carcinoma cell line,Liver,Mammary gland,Ovary,Prostate adenocarcino
Backgroundneuropilin 2(NRP2) Homo sapiens This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],