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Cell Signal Transduction Research Antibodies
VHR Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight20350Da
Protein NameDual specificity protein phosphatase 3
Human Gene Id1845
Human Swiss Prot NoP51452
Mouse Gene Id72349
Mouse Swiss Prot NoQ9D7X3
SpecificityVHR Polyclonal Antibody detects endogenous levels of VHR protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameDUSP3; VHR; Dual specificity protein phosphatase 3; Dual specificity protein phosphatase VHR; Vaccinia H1-related phosphatase; VHR
Observed Band(KD)21
Functioncatalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:This protein shows activity both toward tyrosine-protein phosphate as well as with serine-protein phosphate.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,
Subcellular LocationNucleus .
ExpressionDuodenum,Uterus,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human DUSP3. AA range:136-185
Gene NameDUSP3
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Backgrounddual specificity phosphatase 3(DUSP3) Homo sapiens The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast ca
Conjugated Antibody
This product is also available conjugated. Format: E20-75228-Conjugate. Price: $485 / Size: 100μl.
E20-75228-FITC$485 / 100μlE20-75228-Biotin$485 / 100μlE20-75228-HRP$485 / 100μlE20-75228-AP$485 / 100μlE20-75228-AF350$485 / 100μlE20-75228-AF405M$485 / 100μlE20-75228-AF488$485 / 100μlE20-75228-AF514$485 / 100μlE20-75228-AF532$485 / 100μlE20-75228-AF555$485 / 100μlE20-75228-AF568$485 / 100μlE20-75228-AF405S$485 / 100μlE20-75228-AF405L$485 / 100μlE20-75228-AF546$485 / 100μlE20-75228-AF594$485 / 100μlE20-75228-AF610$485 / 100μlE20-75228-AF635$485 / 100μlE20-75228-AF647$485 / 100μlE20-75228-AF680$485 / 100μlE20-75228-AF700$485 / 100μlE20-75228-AF750$485 / 100μlE20-75228-AF790$485 / 100μlE20-75228-APC$485 / 100μlE20-75228-PE$485 / 100μlE20-75228-Cy3$485 / 100μlE20-75228-Cy5$485 / 100μlE20-75228-Cy5.5$485 / 100μlE20-75228-Cy7$485 / 100μlE20-75228-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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