Product Information
Molecular Weight74141Da
Protein NameHistidine decarboxylase
Human Gene Id3067
Human Swiss Prot NoP19113
Mouse Gene Id15186
Mouse Swiss Prot NoP23738
Rat Swiss Prot NoP16453
SpecificityHDC Polyclonal Antibody detects endogenous levels of HDC protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameHDC; Histidine decarboxylase; HDC
Observed Band(KD)72
Functioncatalytic activity:L-histidine = histamine + CO(2).,cofactor:Pyridoxal phosphate.,pathway:Amine and polyamine biosynthesis; histamine biosynthesis; histamine from L-histidine: step 1/1.,similarity:Belongs to the group II decarboxylase family.,subunit:Homodimer.,
Subcellular Locationcytosol,
ExpressionLeukemia,
Backgroundhistidine decarboxylase(HDC) Homo sapiens This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010],