Protein C Polyclonal Antibody

Name: Protein C Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75221
Price: 225 USD
Availability: InStock

E20-75221Cite ID: EN0055354Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight52071Da

Protein NameVitamin K-dependent protein C

Human Gene Id5624

Human Swiss Prot NoP04070

Mouse Swiss Prot NoP33587

SpecificityProtein C Polyclonal Antibody detects endogenous levels of Protein C protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NamePROC; Vitamin K-dependent protein C; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV

Observed Band(KD)52

Functioncatalytic activity:Degradation of blood coagulation factors Va and VIIIa.,disease:Defects in PROC are the cause of protein C deficiency autosomal dominant (ADPROCD) [MIM:176860]. ADPROCD is a cause of hereditary thrombophilia, a hemostatic disorder characterized by impaired regulation of blood coagulation and a tendency to recurrent venous thrombosis. However, many adults with heterozygous disease may be asymptomatic. Individuals with decreased amounts of protein C are classically referred to as having type I protein C deficiency and those with normal amounts of a functionally defective protein as having type II deficiency.,disease:Defects in PROC are the cause of protein C deficiency autosomal recessive (ARPROCD) [MIM:612304]. ARPROCD results in a thrombotic condition that can manifest as a severe neonatal disorder or as a milder disorder with late-onset thrombophilia. The severe form l

Subcellular LocationSecreted . Golgi apparatus . Endoplasmic reticulum .

ExpressionPlasma; synthesized in the liver.

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human PROC. AA range:181-230

Gene NamePROC

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Backgroundprotein C, inactivator of coagulation factors Va and VIIIa(PROC) Homo sapiens This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75221-Conjugate. Price: $485 / Size: 100μl.

E20-75221-FITC$485 / 100μlE20-75221-Biotin$485 / 100μlE20-75221-HRP$485 / 100μlE20-75221-AP$485 / 100μlE20-75221-AF350$485 / 100μlE20-75221-AF405M$485 / 100μlE20-75221-AF488$485 / 100μlE20-75221-AF514$485 / 100μlE20-75221-AF532$485 / 100μlE20-75221-AF555$485 / 100μlE20-75221-AF568$485 / 100μlE20-75221-AF405S$485 / 100μlE20-75221-AF405L$485 / 100μlE20-75221-AF546$485 / 100μlE20-75221-AF594$485 / 100μlE20-75221-AF610$485 / 100μlE20-75221-AF635$485 / 100μlE20-75221-AF647$485 / 100μlE20-75221-AF680$485 / 100μlE20-75221-AF700$485 / 100μlE20-75221-AF750$485 / 100μlE20-75221-AF790$485 / 100μlE20-75221-APC$485 / 100μlE20-75221-PE$485 / 100μlE20-75221-Cy3$485 / 100μlE20-75221-Cy5$485 / 100μlE20-75221-Cy5.5$485 / 100μlE20-75221-Cy7$485 / 100μlE20-75221-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.