MCM3 Polyclonal Antibody

Name: MCM3 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75217
Price: 225 USD
Availability: InStock

E20-75217Cite ID: EN0055350Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight88880Da

Protein NameDNA replication licensing factor MCM3

Human Gene Id4172

Human Swiss Prot NoP25205

Mouse Swiss Prot NoP25206

SpecificityMCM3 Polyclonal Antibody detects endogenous levels of MCM3 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameMCM3; DNA replication licensing factor MCM3; DNA polymerase alpha holoenzyme-associated protein P1; P1-MCM3; RLF subunit beta; p102

Observed Band(KD)89

Functionfunction:Acts as a factor that allows the DNA to undergo a single round of replication per cell cycle. Required for DNA replication and cell proliferation.,miscellaneous:Associated with the replication-specific DNA polymerase alpha.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MCM family.,similarity:Contains 1 MCM domain.,

Subcellular LocationNucleus . Chromosome . Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses. .

ExpressionCervix,Coronary artery,Epithelium,Lymph,Osteosarcoma,Pancre

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human MCM3. AA range:641-690

Gene NameMCM3

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Backgroundminichromosome maintenance complex component 3(MCM3) Homo sapiens The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75217-Conjugate. Price: $485 / Size: 100μl.

E20-75217-FITC$485 / 100μlE20-75217-Biotin$485 / 100μlE20-75217-HRP$485 / 100μlE20-75217-AP$485 / 100μlE20-75217-AF350$485 / 100μlE20-75217-AF405M$485 / 100μlE20-75217-AF488$485 / 100μlE20-75217-AF514$485 / 100μlE20-75217-AF532$485 / 100μlE20-75217-AF555$485 / 100μlE20-75217-AF568$485 / 100μlE20-75217-AF405S$485 / 100μlE20-75217-AF405L$485 / 100μlE20-75217-AF546$485 / 100μlE20-75217-AF594$485 / 100μlE20-75217-AF610$485 / 100μlE20-75217-AF635$485 / 100μlE20-75217-AF647$485 / 100μlE20-75217-AF680$485 / 100μlE20-75217-AF700$485 / 100μlE20-75217-AF750$485 / 100μlE20-75217-AF790$485 / 100μlE20-75217-APC$485 / 100μlE20-75217-PE$485 / 100μlE20-75217-Cy3$485 / 100μlE20-75217-Cy5$485 / 100μlE20-75217-Cy5.5$485 / 100μlE20-75217-Cy7$485 / 100μlE20-75217-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.