IL-5Rα Polyclonal Antibody

Name: IL-5Rα Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75214
Price: 225 USD
Availability: InStock

E20-75214Cite ID: EN0055347Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight47685Da

Protein NameInterleukin-5 receptor subunit alpha

Human Gene Id3568

Human Swiss Prot NoQ01344

Mouse Swiss Prot NoP21183

SpecificityIL-5Rα Polyclonal Antibody detects endogenous levels of IL-5Rα protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameIL5RA; IL5R; Interleukin-5 receptor subunit alpha; IL-5 receptor subunit alpha; IL-5R subunit alpha; IL-5R-alpha; IL-5RA; CDw125; CD125

Observed Band(KD)47

Functiondomain:The box 1 motif is required for JAK interaction and/or activation.,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.,function:This is the receptor for interleukin-5. The alpha chain binds to IL5.,similarity:Belongs to the type I cytokine receptor family. Type 5 subfamily.,subunit:Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors. Interacts with SDCBP.,tissue specificity:Expressed on eosinophils and basophils.,

Subcellular LocationMembrane; Single-pass type I membrane protein.

ExpressionExpressed on eosinophils and basophils.

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the N-terminal region of human IL5RA. AA range:41-90

Gene NameIL5RA

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Backgroundinterleukin 5 receptor subunit alpha(IL5RA) Homo sapiens The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75214-Conjugate. Price: $485 / Size: 100μl.

E20-75214-FITC$485 / 100μlE20-75214-Biotin$485 / 100μlE20-75214-HRP$485 / 100μlE20-75214-AP$485 / 100μlE20-75214-AF350$485 / 100μlE20-75214-AF405M$485 / 100μlE20-75214-AF488$485 / 100μlE20-75214-AF514$485 / 100μlE20-75214-AF532$485 / 100μlE20-75214-AF555$485 / 100μlE20-75214-AF568$485 / 100μlE20-75214-AF405S$485 / 100μlE20-75214-AF405L$485 / 100μlE20-75214-AF546$485 / 100μlE20-75214-AF594$485 / 100μlE20-75214-AF610$485 / 100μlE20-75214-AF635$485 / 100μlE20-75214-AF647$485 / 100μlE20-75214-AF680$485 / 100μlE20-75214-AF700$485 / 100μlE20-75214-AF750$485 / 100μlE20-75214-AF790$485 / 100μlE20-75214-APC$485 / 100μlE20-75214-PE$485 / 100μlE20-75214-Cy3$485 / 100μlE20-75214-Cy5$485 / 100μlE20-75214-Cy5.5$485 / 100μlE20-75214-Cy7$485 / 100μlE20-75214-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.