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Cell Signal Transduction Research Antibodies

FOXP1 Polyclonal Antibody

E20-75213Cite ID: EN0055346DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight7个亚型 12,55,65 75Da
Protein NameForkhead box protein P1
Human Gene Id27086
Human Swiss Prot NoQ9H334
Mouse Gene Id108655
Mouse Swiss Prot NoP58462
Rat Gene Id297480
Rat Swiss Prot NoQ498D1
SpecificityFOXP1 Polyclonal Antibody detects endogenous levels of FOXP1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameFOXP1; HSPC215; Forkhead box protein P1
Observed Band(KD)75
Functionalternative products:Additional isoforms seem to exist,disease:A chromosomal aberration involving FOXP1 is found in acute lymphoblastic leukemia. Translocation t(9;3)(p13;p14.1) with PAX5.,domain:The leucine-zipper is required for dimerization and transcriptional repression.,function:Transcriptional repressor that plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 fork-head DNA-binding domain.,subunit:Forms homodimers and heterodimers with FOXP2 and FOXP4. Dimerization is required for DNA-binding. Interacts with CTBP1.,
Subcellular LocationNucleus . Not found in the nucleolus. .
ExpressionIsoform 8 is specifically expressed in embryonic stem cells.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human FOXP1. AA range:628-677
Gene NameFOXP1
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Backgroundforkhead box P1(FOXP1) Homo sapiens This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Conjugated Antibody

This product is also available conjugated. Format: E20-75213-Conjugate. Price: $485 / Size: 100μl.

E20-75213-FITC$485 / 100μlE20-75213-Biotin$485 / 100μlE20-75213-HRP$485 / 100μlE20-75213-AP$485 / 100μlE20-75213-AF350$485 / 100μlE20-75213-AF405M$485 / 100μlE20-75213-AF488$485 / 100μlE20-75213-AF514$485 / 100μlE20-75213-AF532$485 / 100μlE20-75213-AF555$485 / 100μlE20-75213-AF568$485 / 100μlE20-75213-AF405S$485 / 100μlE20-75213-AF405L$485 / 100μlE20-75213-AF546$485 / 100μlE20-75213-AF594$485 / 100μlE20-75213-AF610$485 / 100μlE20-75213-AF635$485 / 100μlE20-75213-AF647$485 / 100μlE20-75213-AF680$485 / 100μlE20-75213-AF700$485 / 100μlE20-75213-AF750$485 / 100μlE20-75213-AF790$485 / 100μlE20-75213-APC$485 / 100μlE20-75213-PE$485 / 100μlE20-75213-Cy3$485 / 100μlE20-75213-Cy5$485 / 100μlE20-75213-Cy5.5$485 / 100μlE20-75213-Cy7$485 / 100μlE20-75213-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

FOXP1 Polyclonal Antibody | EnoGene Biotech Co. Ltd