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Cell Signal Transduction Research Antibodies

MIP-1β Polyclonal Antibody

E20-75207Cite ID: EN0055340DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight10212Da
Protein NameC-C motif chemokine 4
Human Gene Id388372
Human Swiss Prot NoP13236
Mouse Swiss Prot NoP14097
SpecificityMIP-1β Polyclonal Antibody detects endogenous levels of MIP-1β protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCCL4; LAG1; MIP1B; SCYA4; C-C motif chemokine 4; G-26 T-lymphocyte-secreted protein; HC21; Lymphocyte activation gene 1 protein; LAG-1; MIP-1-beta(1-69);Macrophage inflammatory protein 1-beta; MIP-1-beta; PAT 744; Protein H400; SIS-gamma; Small-inducible cytokine A4; T-cell activation protein 2; ACT-2
Observed Band(KD)16
Functionalternative products:CCL4L1 and CCL4L2 genes differ in their non-coding regions. Thus, alternative splicing events differ between the two genes,caution:Was originally (PubMed:9521068) thought to be a ligand for CCR8.,function:Chemokine that induces chemotaxis of cells expressing CCR5 or CCR1. Inhibits HIV replication in peripheral blood monocytes that express CCR5.,function:Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR
Subcellular LocationSecreted.
ExpressionBlood,Brain,Lung,Natural killer cell,T-cell,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CCL4. AA range:41-90
Gene NameCCL4
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
BackgroundC-C motif chemokine ligand 4(CCL4) Homo sapiens The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. [provided by RefSeq, Dec 2012],

Conjugated Antibody

This product is also available conjugated. Format: E20-75207-Conjugate. Price: $485 / Size: 100μl.

E20-75207-FITC$485 / 100μlE20-75207-Biotin$485 / 100μlE20-75207-HRP$485 / 100μlE20-75207-AP$485 / 100μlE20-75207-AF350$485 / 100μlE20-75207-AF405M$485 / 100μlE20-75207-AF488$485 / 100μlE20-75207-AF514$485 / 100μlE20-75207-AF532$485 / 100μlE20-75207-AF555$485 / 100μlE20-75207-AF568$485 / 100μlE20-75207-AF405S$485 / 100μlE20-75207-AF405L$485 / 100μlE20-75207-AF546$485 / 100μlE20-75207-AF594$485 / 100μlE20-75207-AF610$485 / 100μlE20-75207-AF635$485 / 100μlE20-75207-AF647$485 / 100μlE20-75207-AF680$485 / 100μlE20-75207-AF700$485 / 100μlE20-75207-AF750$485 / 100μlE20-75207-AF790$485 / 100μlE20-75207-APC$485 / 100μlE20-75207-PE$485 / 100μlE20-75207-Cy3$485 / 100μlE20-75207-Cy5$485 / 100μlE20-75207-Cy5.5$485 / 100μlE20-75207-Cy7$485 / 100μlE20-75207-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

MIP-1β Polyclonal Antibody | EnoGene Biotech Co. Ltd