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Cell Signal Transduction Research Antibodies
Annexin II Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight38604Da
Protein NameAnnexin A2
Human Gene Id302
Human Swiss Prot NoP07355
Mouse Gene Id12306
Mouse Swiss Prot NoP07356
Rat Gene Id56611
Rat Swiss Prot NoQ07936
SpecificityAnnexin II Polyclonal Antibody detects endogenous levels of Annexin II protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameANXA2; ANX2; ANX2L4; CAL1H; LPC2D; Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36
Observed Band(KD)38
Functiondomain:A pair of annexin repeats may form one binding site for calcium and phospholipid.,function:Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.,miscellaneous:It may cross-link plasma membrane phospholipids with actin and the cytoskeleton and be involved with exocytosis.,online information:Red velvet - Issue 86 of September 2007,PTM:Phosphorylation of Tyr-24 enhances heat stress-induced translocation to the cell surface.,similarity:Belongs to the annexin family.,similarity:Contains 4 annexin repeats.,subcellular location:In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism.,s
Subcellular LocationSecreted, extracellular space, extracellular matrix, basement membrane . Melanosome . In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism.
ExpressionBrain,Colon,Colon adenocarcinoma,Epithelium,Osteosarcoma,Pancreas,Pla
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human ANXA2. AA range:51-100
Gene NameANXA2
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundannexin A2(ANXA2) Homo sapiens This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75203-Conjugate. Price: $485 / Size: 100μl.
E20-75203-FITC$485 / 100μlE20-75203-Biotin$485 / 100μlE20-75203-HRP$485 / 100μlE20-75203-AP$485 / 100μlE20-75203-AF350$485 / 100μlE20-75203-AF405M$485 / 100μlE20-75203-AF488$485 / 100μlE20-75203-AF514$485 / 100μlE20-75203-AF532$485 / 100μlE20-75203-AF555$485 / 100μlE20-75203-AF568$485 / 100μlE20-75203-AF405S$485 / 100μlE20-75203-AF405L$485 / 100μlE20-75203-AF546$485 / 100μlE20-75203-AF594$485 / 100μlE20-75203-AF610$485 / 100μlE20-75203-AF635$485 / 100μlE20-75203-AF647$485 / 100μlE20-75203-AF680$485 / 100μlE20-75203-AF700$485 / 100μlE20-75203-AF750$485 / 100μlE20-75203-AF790$485 / 100μlE20-75203-APC$485 / 100μlE20-75203-PE$485 / 100μlE20-75203-Cy3$485 / 100μlE20-75203-Cy5$485 / 100μlE20-75203-Cy5.5$485 / 100μlE20-75203-Cy7$485 / 100μlE20-75203-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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