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Cell Signal Transduction Research Antibodies
Cdc34 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight26737Da
Protein NameUbiquitin-conjugating enzyme E2 R1
Human Gene Id997
Human Swiss Prot NoP49427
Mouse Gene Id216150
Mouse Swiss Prot NoQ8CFI2
SpecificityCdc34 Polyclonal Antibody detects endogenous levels of Cdc34 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCDC34; UBCH3; UBE2R1; Ubiquitin-conjugating enzyme E2 R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; Ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protein ligase R1
Observed Band(KD)34
Functioncatalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.,function:Catalyzes the covalent attachment of ubiquitin to other proteins. May be involved in degradation of katenin.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the ubiquitin-conjugating enzyme family.,subunit:Interacts with SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex. When phosphorylated, interacts with beta-TrCP (BTRC).,
Subcellular LocationCytoplasm. Nucleus. The phosphorylation of the C-terminal tail plays an important role in mediating nuclear localization. Colocalizes with beta-tubulin on mitotic spindles in anaphase.
ExpressionExpressed in testes during spermatogenesis to regulate repression of cAMP-induced transcription.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CDC34. AA range:121-170
Gene NameCDC34
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Backgroundcell division cycle 34(CDC34) Homo sapiens The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75189-Conjugate. Price: $485 / Size: 100μl.
E20-75189-FITC$485 / 100μlE20-75189-Biotin$485 / 100μlE20-75189-HRP$485 / 100μlE20-75189-AP$485 / 100μlE20-75189-AF350$485 / 100μlE20-75189-AF405M$485 / 100μlE20-75189-AF488$485 / 100μlE20-75189-AF514$485 / 100μlE20-75189-AF532$485 / 100μlE20-75189-AF555$485 / 100μlE20-75189-AF568$485 / 100μlE20-75189-AF405S$485 / 100μlE20-75189-AF405L$485 / 100μlE20-75189-AF546$485 / 100μlE20-75189-AF594$485 / 100μlE20-75189-AF610$485 / 100μlE20-75189-AF635$485 / 100μlE20-75189-AF647$485 / 100μlE20-75189-AF680$485 / 100μlE20-75189-AF700$485 / 100μlE20-75189-AF750$485 / 100μlE20-75189-AF790$485 / 100μlE20-75189-APC$485 / 100μlE20-75189-PE$485 / 100μlE20-75189-Cy3$485 / 100μlE20-75189-Cy5$485 / 100μlE20-75189-Cy5.5$485 / 100μlE20-75189-Cy7$485 / 100μlE20-75189-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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