SSX Polyclonal Antibody

Name: SSX Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75185
Price: 225 USD
Availability: InStock

E20-75185Cite ID: EN0055318Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight(Da):21931/21620/21697/21858/21660/21688/21591/21859/21553

Protein NameProtein SSX1/Protein SSX2/Protein SSX3/Protein SSX4/Protein SSX5/Protein SSX6/ Protein SSX7/Protein SSX8/Protein SSX9

Human Gene Id6756

Human Swiss Prot NoQ16384

SpecificitySSX Polyclonal Antibody detects endogenous levels of SSX protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameSSX1; Protein SSX1; Cancer/testis antigen 5.1; CT5.1; Synovial sarcoma, X breakpoint 1; SSX2; SSX2A; SSX2B; Protein SSX2; Cancer/testis antigen 5.2; CT5.2; Synovial sarcoma, X breakpoint 2; Tumor antigen HOM-MEL-40; SSX3; Protein SSX3;Cancer/testis antigen 5.3; CT5.3; SSX4; SSX4A; SSX4B; Protein SSX4; Cancer/testis antigen 5.4; CT5.4; SSX5; Protein SSX5; SSX6; Putative protein SSX6; SSX7; Protein SSX7; SSX8; Protein SSX8; SSX9; Protein SSX9

Observed Band(KD)25

Functiondisease:A chromosomal aberration involving SSX1 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).,function:Could act as a modulator of transcription.,similarity:Belongs to the SSX family.,similarity:Contains 1 KRAB-related domain.,tissue specificity:Expressed at high level in the testis. Expressed at low level in thyroid. Not detected in tonsil, colon, lung, spleen, prostate, kidney, striated and smooth muscles. Detected in rhabdomyosarcoma and fibrosarcoma cell lines. Not detected in mesenchymal and epithelial cell lines.,tissue specificity:Not detected in any normal or tumor tissues.

Subcellular Locationnucleus

ExpressionFibrosarcoma,Placenta,Skin,Synovial sarcoma

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human SSX1/2/3/4/5/6/7/8/9. AA range:139-188

Gene NameSSX1/SSX2/SSX3/SSX4/SSX5/SSX6/SSX7/SSX8/SSX9

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

BackgroundSSX family member 1(SSX1) Homo sapiens The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX2 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2013].

Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:100.

Western blot analysis of lysate from 22RV-1 cells, using SSX1/2/3/4/5/6/7/8/9 Antibody.

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75185-Conjugate. Price: $485 / Size: 100μl.

E20-75185-FITC$485 / 100μlE20-75185-Biotin$485 / 100μlE20-75185-HRP$485 / 100μlE20-75185-AP$485 / 100μlE20-75185-AF350$485 / 100μlE20-75185-AF405M$485 / 100μlE20-75185-AF488$485 / 100μlE20-75185-AF514$485 / 100μlE20-75185-AF532$485 / 100μlE20-75185-AF555$485 / 100μlE20-75185-AF568$485 / 100μlE20-75185-AF405S$485 / 100μlE20-75185-AF405L$485 / 100μlE20-75185-AF546$485 / 100μlE20-75185-AF594$485 / 100μlE20-75185-AF610$485 / 100μlE20-75185-AF635$485 / 100μlE20-75185-AF647$485 / 100μlE20-75185-AF680$485 / 100μlE20-75185-AF700$485 / 100μlE20-75185-AF750$485 / 100μlE20-75185-AF790$485 / 100μlE20-75185-APC$485 / 100μlE20-75185-PE$485 / 100μlE20-75185-Cy3$485 / 100μlE20-75185-Cy5$485 / 100μlE20-75185-Cy5.5$485 / 100μlE20-75185-Cy7$485 / 100μlE20-75185-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.