Product Information
Molecular Weight23989DaObserved Band:28KD
Protein NameFibroblast growth factor 18
Human Gene Id8817
Human Swiss Prot NoO76093
Mouse Gene Id14172
Mouse Swiss Prot NoO89101
Rat Gene Id29369
Rat Swiss Prot NoO88182
SpecificityFGF-18 Polyclonal Antibody detects endogenous levels of FGF-18 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameFGF18; Fibroblast growth factor 18; FGF-18; zFGF5
Functionfunction:Stimulates hepatic and intestinal proliferation.,similarity:Belongs to the heparin-binding growth factors family.,
Subcellular Locationextracellular region,extracellular space,nucleolus,
ExpressionLung,Ovary,,
Backgroundfibroblast growth factor 18(FGF18) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures. [provided by RefSeq, Jul 2008],