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Cell Signal Transduction Research Antibodies

FGF-9 Polyclonal Antibody

E20-75179Cite ID: EN0055312DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight23441DaObserved Band:23KD
Protein NameFibroblast growth factor 9
Human Gene Id2254
Human Swiss Prot NoP31371
Mouse Gene Id14180
Mouse Swiss Prot NoP54130
Rat Gene Id25444
Rat Swiss Prot NoP36364
SpecificityFGF-9 Polyclonal Antibody detects endogenous levels of FGF-9 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameFGF9; Fibroblast growth factor 9; FGF-9; Glia-activating factor; GAF; Heparin-binding growth factor 9; HBGF-9
Functiondisease:The continuous overexpression of GAFS may lead to malignant cell growth caused by an autocrine loop.,function:May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.,PTM:N-glycosylated.,PTM:Three molecular species were found (30 kDa, 29 kDa and 25 kDa), cleaved at Leu-4, Val-13 and Ser-34 respectively. The smaller ones might be products of proteolytic digestion. Furthermore, there may be a functional signal sequence in the 30 kDa species which is uncleavable in the secretion step.,similarity:Belongs to the heparin-binding growth factors family.,subunit:Monomer.,tissue specificity:Glial cells.,
Subcellular Locationextracellular region,basement membrane,extracellular space,cytoplasm,extracellular exosome,
ExpressionForeskin,Glial tumor,,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human FGF9. AA range:141-190
Gene NameFGF9
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Backgroundfibroblast growth factor 9(FGF9) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis. [provided by RefSeq, Jul 2008],

Conjugated Antibody

This product is also available conjugated. Format: E20-75179-Conjugate. Price: $485 / Size: 100μl.

E20-75179-FITC$485 / 100μlE20-75179-Biotin$485 / 100μlE20-75179-HRP$485 / 100μlE20-75179-AP$485 / 100μlE20-75179-AF350$485 / 100μlE20-75179-AF405M$485 / 100μlE20-75179-AF488$485 / 100μlE20-75179-AF514$485 / 100μlE20-75179-AF532$485 / 100μlE20-75179-AF555$485 / 100μlE20-75179-AF568$485 / 100μlE20-75179-AF405S$485 / 100μlE20-75179-AF405L$485 / 100μlE20-75179-AF546$485 / 100μlE20-75179-AF594$485 / 100μlE20-75179-AF610$485 / 100μlE20-75179-AF635$485 / 100μlE20-75179-AF647$485 / 100μlE20-75179-AF680$485 / 100μlE20-75179-AF700$485 / 100μlE20-75179-AF750$485 / 100μlE20-75179-AF790$485 / 100μlE20-75179-APC$485 / 100μlE20-75179-PE$485 / 100μlE20-75179-Cy3$485 / 100μlE20-75179-Cy5$485 / 100μlE20-75179-Cy5.5$485 / 100μlE20-75179-Cy7$485 / 100μlE20-75179-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.