Product Information
Molecular Weight23499DaObserved Band:23KD
Protein NameFibroblast growth factor 20
Human Gene Id26281
Human Swiss Prot NoQ9NP95
Mouse Gene Id80857
Mouse Swiss Prot NoQ9ESL9
Rat Gene Id66017
Rat Swiss Prot NoQ9EST9
SpecificityFGF-20 Polyclonal Antibody detects endogenous levels of FGF-20 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameFGF20; Fibroblast growth factor 20; FGF-20
Functionfunction:Neurotrophic factor that regulates central nervous development and function.,similarity:Belongs to the heparin-binding growth factors family.,tissue specificity:Predominantly expressed in the cerebellum.,
Subcellular Locationextracellular region,intracellular,
ExpressionBrain,PCR rescued clones,,
Backgroundfibroblast growth factor 20(FGF20) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility. [provided by RefSeq, Oct 2009],