Product Information
Molecular Weight:47222DaObserved Band:47KD
Protein Name:Inositol polyphosphate multikinase
Human Gene Id:253430
Human Swiss Prot No:Q8NFU5
Mouse Gene Id:69718
Mouse Swiss Prot No:Q7TT16
Rat Gene Id:171458
Rat Swiss Prot No:Q99NI4
Specificity:IPMK Polyclonal Antibody detects endogenous levels of IPMK protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Storage Stability:-20°C/1 year
Other Name:IPMK; IMPK; Inositol polyphosphate multikinase; Inositol 1; 3,4,6-tetrakisphosphate 5-kinase
Function:catalytic activity:ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate.,catalytic activity:ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate.,function:Inositol phosphate kinase with a broad substrate specificity. Has a preference for inositol-1,4,5-trisphosphate (Ins(1,4,5)P3) and inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4).,similarity:Belongs to the inositol phosphokinase (IPK) family.,tissue specificity:Ubiquitous, with the highest expression in skeletal muscle, liver, placenta, lung, peripheral blood leukocytes, kidney, spleen and colon.,
Subcellular Location:nucleus,nucleoplasm,nucleolus,
Expression:Brain,,
Background:inositol polyphosphate multikinase(IPMK) Homo sapiens This gene encodes a member of the inositol phosphokinase family. The encoded protein has 3-kinase, 5-kinase and 6-kinase activities on phosphorylated inositol substrates. The encoded protein plays an important role in the biosynthesis of inositol 1,3,4,5,6-pentakisphosphate, and has a preferred 5-kinase activity. This gene may play a role in nuclear mRNA export. Pseudogenes of this gene are located on the long arm of chromosome 13 and the short arm of chromosome 19. [provided by RefSeq, Dec 2010],