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Cell Signal Transduction Research Antibodies

CD66e Polyclonal Antibody

E20-75172Cite ID: EN0055305DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight76796DaObserved Band:76KD
Protein NameCarcinoembryonic antigen-related cell adhesion molecule 5
Human Gene Id1048
Human Swiss Prot NoP06731
Mouse Swiss Prot NoQ3UKK2
SpecificityCD66e Polyclonal Antibody detects endogenous levels of CD66e protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCEACAM5: CEA: Carcinoembryonic antigen-related cell adhesion molecule 5: Carcinoembryonic antigen: CEA: Meconium antigen 100: CD66e
Functionfunction:Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.,PTM:Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.,similarity:Belongs to the immunoglobulin superfamily. CEA family.,similarity:Contains 7 Ig-like (immunoglobulin-like) domains.,subunit:Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.,tissue specificity:Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.,
Subcellular LocationCell membrane : Lipid-anchor, GPI-anchor . Apical cell membrane . Cell surface . Localized to the apical glycocalyx surface. .
ExpressionExpressed in columnar epithelial and goblet cells of the colon (at protein level) (PubMed:10436421). Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CEACAM5. AA range:481-530
Gene NameCEACAM5
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Backgroundcarcinoembryonic antigen related cell adhesion molecule 5(CEACAM5) Homo sapiens This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015],

Conjugated Antibody

This product is also available conjugated. Format: E20-75172-Conjugate. Price: $485 / Size: 100μl.

E20-75172-FITC$485 / 100μlE20-75172-Biotin$485 / 100μlE20-75172-HRP$485 / 100μlE20-75172-AP$485 / 100μlE20-75172-AF350$485 / 100μlE20-75172-AF405M$485 / 100μlE20-75172-AF488$485 / 100μlE20-75172-AF514$485 / 100μlE20-75172-AF532$485 / 100μlE20-75172-AF555$485 / 100μlE20-75172-AF568$485 / 100μlE20-75172-AF405S$485 / 100μlE20-75172-AF405L$485 / 100μlE20-75172-AF546$485 / 100μlE20-75172-AF594$485 / 100μlE20-75172-AF610$485 / 100μlE20-75172-AF635$485 / 100μlE20-75172-AF647$485 / 100μlE20-75172-AF680$485 / 100μlE20-75172-AF700$485 / 100μlE20-75172-AF750$485 / 100μlE20-75172-AF790$485 / 100μlE20-75172-APC$485 / 100μlE20-75172-PE$485 / 100μlE20-75172-Cy3$485 / 100μlE20-75172-Cy5$485 / 100μlE20-75172-Cy5.5$485 / 100μlE20-75172-Cy7$485 / 100μlE20-75172-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

CD66e Polyclonal Antibody | EnoGene Biotech Co. Ltd