CBP 35 Polyclonal Antibody

Name: CBP 35 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75168
Price: 225 USD
Availability: InStock

E20-75168Cite ID: EN0055301Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight26188DaObserved Band:26KD

Protein NameGalectin-3

Human Gene Id3958

Human Swiss Prot NoP17931

Mouse Swiss Prot NoP16110

SpecificityCBP 35 Polyclonal Antibody detects endogenous levels of CBP 35 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameLGALS3; MAC2; Galectin-3; Gal-3; 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigen

Functionfunction:Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis.,online information:Galectin-3,similarity:Contains 1 galectin domain.,subcellular location:Cytoplasmic in adenomas and carcinomas. May be secreted by a non-classical secretory pathway and associate with the cell surface.,subunit:Probably forms homo- or heterodimers. Interacts with DMBT1 (By similarity). Forms a complex with the ITGA3, ITGB1 and CSPG4. Interacts with LGALS3BP, LYPD3, CYHR1 and UACA.,tissue specificity:A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages.,

Subcellular LocationCytoplasm . Nucleus. Secreted . Secreted by a non-classical secretory pathway and associates with the cell surface. Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). .

ExpressionA major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes.,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human LGALS3. AA range:201-250

Gene NameLGALS3

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Backgroundgalectin 3(LGALS3) Homo sapiens This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75168-Conjugate. Price: $485 / Size: 100μl.

E20-75168-FITC$485 / 100μlE20-75168-Biotin$485 / 100μlE20-75168-HRP$485 / 100μlE20-75168-AP$485 / 100μlE20-75168-AF350$485 / 100μlE20-75168-AF405M$485 / 100μlE20-75168-AF488$485 / 100μlE20-75168-AF514$485 / 100μlE20-75168-AF532$485 / 100μlE20-75168-AF555$485 / 100μlE20-75168-AF568$485 / 100μlE20-75168-AF405S$485 / 100μlE20-75168-AF405L$485 / 100μlE20-75168-AF546$485 / 100μlE20-75168-AF594$485 / 100μlE20-75168-AF610$485 / 100μlE20-75168-AF635$485 / 100μlE20-75168-AF647$485 / 100μlE20-75168-AF680$485 / 100μlE20-75168-AF700$485 / 100μlE20-75168-AF750$485 / 100μlE20-75168-AF790$485 / 100μlE20-75168-APC$485 / 100μlE20-75168-PE$485 / 100μlE20-75168-Cy3$485 / 100μlE20-75168-Cy5$485 / 100μlE20-75168-Cy5.5$485 / 100μlE20-75168-Cy7$485 / 100μlE20-75168-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.