World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
CPE Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight53151DaObserved Band:53KD
Protein NameCarboxypeptidase E
Human Gene Id1363
Human Swiss Prot NoP16870
Mouse Gene Id12876
Mouse Swiss Prot NoQ00493
Rat Gene Id25669
Rat Swiss Prot NoP15087
SpecificityCPE Polyclonal Antibody detects endogenous levels of CPE protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCPE; Carboxypeptidase E; CPE; Carboxypeptidase H; CPH; Enkephalin convertase; Prohormone-processing carboxypeptidase
Functioncatalytic activity:Release of C-terminal arginine or lysine residues from polypeptides.,cofactor:Binds 1 zinc ion per subunit.,function:Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing. Processes proinsulin.,similarity:Belongs to the peptidase M14 family.,subcellular location:Secretory granules of pancreatic islets, adrenal gland, pituitary and brain.,
Subcellular Location[Isoform 1]: Cytoplasmic vesicle, secretory vesicle . Cytoplasmic vesicle, secretory vesicle membrane ; Peripheral membrane protein . Secreted . Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions. .
ExpressionBrain,Colon,Eye,,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human CPE. AA range:271-320
Gene NameCPE
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundcarboxypeptidase E(CPE) Homo sapiens This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes. [provided by RefSeq, Nov 2015],
Conjugated Antibody
This product is also available conjugated. Format: E20-75167-Conjugate. Price: $485 / Size: 100μl.
E20-75167-FITC$485 / 100μlE20-75167-Biotin$485 / 100μlE20-75167-HRP$485 / 100μlE20-75167-AP$485 / 100μlE20-75167-AF350$485 / 100μlE20-75167-AF405M$485 / 100μlE20-75167-AF488$485 / 100μlE20-75167-AF514$485 / 100μlE20-75167-AF532$485 / 100μlE20-75167-AF555$485 / 100μlE20-75167-AF568$485 / 100μlE20-75167-AF405S$485 / 100μlE20-75167-AF405L$485 / 100μlE20-75167-AF546$485 / 100μlE20-75167-AF594$485 / 100μlE20-75167-AF610$485 / 100μlE20-75167-AF635$485 / 100μlE20-75167-AF647$485 / 100μlE20-75167-AF680$485 / 100μlE20-75167-AF700$485 / 100μlE20-75167-AF750$485 / 100μlE20-75167-AF790$485 / 100μlE20-75167-APC$485 / 100μlE20-75167-PE$485 / 100μlE20-75167-Cy3$485 / 100μlE20-75167-Cy5$485 / 100μlE20-75167-Cy5.5$485 / 100μlE20-75167-Cy7$485 / 100μlE20-75167-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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