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Cell Signal Transduction Research Antibodies
TALL-1 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight31223DaObserved Band:32KD
Protein NameTumor necrosis factor ligand superfamily member 13B
Human Gene Id10673
Human Swiss Prot NoQ9Y275
Mouse Swiss Prot NoQ9WU72
SpecificityTALL-1 Polyclonal Antibody detects endogenous levels of TALL-1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF;Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1; CD257
Functionfunction:Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B-and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.,induction:Up-regulated by exposure to interferon-gamma. Down-regulated by phorbol myristate acetate/ionomycin treatment.,online information:Proteic grace - Issue 77 of December 2006,PTM:N-glycosylated.,PTM:The soluble form derives from the membrane form by proteolytic processing.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer.,tissue specificity:Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bo
Subcellular LocationCell membrane; Single-pass type II membrane protein.; [Tumor necrosis factor ligand superfamily member 13b, soluble form]: Secreted.
ExpressionAbundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T-cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas. Isoform 2 is expressed in many myeloid cell lines.,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human TNFSF13B. AA range:151-200
Gene NameTNFSF13B
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Backgroundtumor necrosis factor superfamily member 13b(TNFSF13B) Homo sapiens The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011],
Conjugated Antibody
This product is also available conjugated. Format: E20-75166-Conjugate. Price: $485 / Size: 100μl.
E20-75166-FITC$485 / 100μlE20-75166-Biotin$485 / 100μlE20-75166-HRP$485 / 100μlE20-75166-AP$485 / 100μlE20-75166-AF350$485 / 100μlE20-75166-AF405M$485 / 100μlE20-75166-AF488$485 / 100μlE20-75166-AF514$485 / 100μlE20-75166-AF532$485 / 100μlE20-75166-AF555$485 / 100μlE20-75166-AF568$485 / 100μlE20-75166-AF405S$485 / 100μlE20-75166-AF405L$485 / 100μlE20-75166-AF546$485 / 100μlE20-75166-AF594$485 / 100μlE20-75166-AF610$485 / 100μlE20-75166-AF635$485 / 100μlE20-75166-AF647$485 / 100μlE20-75166-AF680$485 / 100μlE20-75166-AF700$485 / 100μlE20-75166-AF750$485 / 100μlE20-75166-AF790$485 / 100μlE20-75166-APC$485 / 100μlE20-75166-PE$485 / 100μlE20-75166-Cy3$485 / 100μlE20-75166-Cy5$485 / 100μlE20-75166-Cy5.5$485 / 100μlE20-75166-Cy7$485 / 100μlE20-75166-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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