World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
Apelin Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight8569DaObserved Band:16KD
Protein NameApelin
Human Gene Id8862
Human Swiss Prot NoQ9ULZ1
Mouse Gene Id30878
Mouse Swiss Prot NoQ9R0R4
Rat Gene Id58812
Rat Swiss Prot NoQ9R0R3
SpecificityApelin Polyclonal Antibody detects endogenous levels of Apelin protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameAPLN; APEL; Apelin; APJ endogenous ligand
Functionfunction:Endogenous ligand for APJ, an alternative coreceptor with CD4 for HIV-1 infection. Inhibits HIV-1 entry in cells coexpressing CD4 and APJ. Apelin-36 has a greater inhibitory activity on HIV infection than other synthetic apelin derivatives. The oral intake in the colostrum and the milk could have a role in the modulation of the immune responses in neonates. May also have a role in the central control of body fluid homeostasis by influencing AVP release and drinking behavior.,PTM:Several active peptides may be produced by proteolytic processing of the peptide precursor.,similarity:Belongs to the apelin family.,tissue specificity:Expressed in the brain with highest levels in the frontal cortex, thalamus, hypothalamus and midbrain. Secreted by the mammary gland into the colostrum and the milk.,
Subcellular LocationSecreted . Secreted, extracellular space . Abundantly secreted in the colostrum. Lower level in milk. Decreases rapidly within several days after parturition in milk, but is still detectable even in commercial milk. .
ExpressionExpressed in the brain with highest levels in the frontal cortex, thalamus, hypothalamus and midbrain (PubMed:10617103). Secreted by the mammary gland into the colostrum and the milk.,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human APLN. AA range:28-77
Gene NameAPLN
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Backgroundapelin(APLN) Homo sapiens This gene encodes a peptide that functions as an endogenous ligand for the G-protein coupled apelin receptor. The encoded preproprotein is proteolytically processed into biologically active C-terminal peptide fragments. These peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. [provided by RefSeq, Feb 2016],
Conjugated Antibody
This product is also available conjugated. Format: E20-75163-Conjugate. Price: $485 / Size: 100μl.
E20-75163-FITC$485 / 100μlE20-75163-Biotin$485 / 100μlE20-75163-HRP$485 / 100μlE20-75163-AP$485 / 100μlE20-75163-AF350$485 / 100μlE20-75163-AF405M$485 / 100μlE20-75163-AF488$485 / 100μlE20-75163-AF514$485 / 100μlE20-75163-AF532$485 / 100μlE20-75163-AF555$485 / 100μlE20-75163-AF568$485 / 100μlE20-75163-AF405S$485 / 100μlE20-75163-AF405L$485 / 100μlE20-75163-AF546$485 / 100μlE20-75163-AF594$485 / 100μlE20-75163-AF610$485 / 100μlE20-75163-AF635$485 / 100μlE20-75163-AF647$485 / 100μlE20-75163-AF680$485 / 100μlE20-75163-AF700$485 / 100μlE20-75163-AF750$485 / 100μlE20-75163-AF790$485 / 100μlE20-75163-APC$485 / 100μlE20-75163-PE$485 / 100μlE20-75163-Cy3$485 / 100μlE20-75163-Cy5$485 / 100μlE20-75163-Cy5.5$485 / 100μlE20-75163-Cy7$485 / 100μlE20-75163-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits