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Cell Signal Transduction Research Antibodies

HSP40-4 Polyclonal Antibody

E20-75162Cite ID: EN0055295DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight44868DaObserved Band:44KD
Protein NameDnaJ homolog subfamily A member 1
Human Gene Id3301
Human Swiss Prot NoP31689
Mouse Gene Id15502
Mouse Swiss Prot NoP63037
Rat Gene Id65028
Rat Swiss Prot NoP63036
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameDNAJA1; DNAJ2; HDJ2; HSJ2; HSPF4; DnaJ homolog subfamily A member 1; DnaJ protein homolog 2; HSDJ; Heat shock 40 kDa protein 4; Heat shock protein J2; HSJ-2; Human DnaJ protein 2; hDj-2
Functionfunction:Co-chaperone of Hsc70. Seems to play a role in protein import into mitochondria.,similarity:Contains 1 CR-type zinc finger.,similarity:Contains 1 J domain.,
Subcellular LocationMembrane ; Lipid-anchor . Cytoplasm . Microsome . Nucleus . Cytoplasm, perinuclear region . Mitochondrion . Primarily associated with microsomes. A minor proportion is associated with mitochondria (By similarity). Primarily cytoplasmic. A minor proportion is associated with nuclei. .
ExpressionUbiquitous. Isoform 2 is highly expressed in testis and lung, but detected at low levels in thymus, prostate, colon and liver.,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human DNAJA1. AA range:71-120Specificity:HSP40-4 Polyclonal Antibody detects endogenous levels of HSP40-4 protein.
Gene NameDNAJA1
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
BackgroundDnaJ heat shock protein family (Hsp40) member A1(DNAJA1) Homo sapiens This gene encodes a member of the DnaJ family of proteins, which act as heat shock protein 70 cochaperones. Heat shock proteins facilitate protein folding, trafficking, prevention of aggregation, and proteolytic degradation. Members of this family are characterized by a highly conserved N-terminal J domain, a glycine/phenylalanine-rich region, four CxxCxGxG zinc finger repeats, and a C-terminal substrate-binding domain. The J domain mediates the interaction with heat shock protein 70 to recruit substrates and regulate ATP hydrolysis activity. In humans, this gene has been implicated in positive regulation of virus replication through co-option by the influenza A virus. Several pseudogenes of this gene are found on other chromosomes. [provided by RefSeq, Sep 2015],

Conjugated Antibody

This product is also available conjugated. Format: E20-75162-Conjugate. Price: $485 / Size: 100μl.

E20-75162-FITC$485 / 100μlE20-75162-Biotin$485 / 100μlE20-75162-HRP$485 / 100μlE20-75162-AP$485 / 100μlE20-75162-AF350$485 / 100μlE20-75162-AF405M$485 / 100μlE20-75162-AF488$485 / 100μlE20-75162-AF514$485 / 100μlE20-75162-AF532$485 / 100μlE20-75162-AF555$485 / 100μlE20-75162-AF568$485 / 100μlE20-75162-AF405S$485 / 100μlE20-75162-AF405L$485 / 100μlE20-75162-AF546$485 / 100μlE20-75162-AF594$485 / 100μlE20-75162-AF610$485 / 100μlE20-75162-AF635$485 / 100μlE20-75162-AF647$485 / 100μlE20-75162-AF680$485 / 100μlE20-75162-AF700$485 / 100μlE20-75162-AF750$485 / 100μlE20-75162-AF790$485 / 100μlE20-75162-APC$485 / 100μlE20-75162-PE$485 / 100μlE20-75162-Cy3$485 / 100μlE20-75162-Cy5$485 / 100μlE20-75162-Cy5.5$485 / 100μlE20-75162-Cy7$485 / 100μlE20-75162-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.