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Cell Signal Transduction Research Antibodies

Catalase Polyclonal Antibody

E20-75155Cite ID: EN0055288DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight59756Da
Protein NameCatalase
Human Gene Id847
Human Swiss Prot NoP04040
Mouse Gene Id12359
Mouse Swiss Prot NoP24270
Rat Gene Id24248
Rat Swiss Prot NoP04762
SpecificityCatalase Polyclonal Antibody detects endogenous levels of Catalase protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCAT; Catalase
Functioncatalytic activity:2 H(2)O(2) = O(2) + 2 H(2)O.,cofactor:Heme group.,cofactor:NADP.,disease:Defects in CAT are the cause of acatalasia (ACATLAS) [MIM:115500]; also known as acatalasemia. This disease is characterized by absence of catalase activity in red cells and is often associated with ulcerating oral lesions.,function:Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.,online information:Catalase entry,PTM:The N-terminus is blocked.,similarity:Belongs to the catalase family.,subunit:Homotetramer.,
Subcellular LocationPeroxisome.
ExpressionBrain,Cajal-Retzius cell,Erythrocyte,Eye,Fibroblast,Kidney,Liver,Placenta,Platelet,Skin,Uterus,,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human Catalase. AA range:361-410
Gene NameCAT
DilutionImmunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Backgroundcatalase(CAT) Homo sapiens This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009],

Conjugated Antibody

This product is also available conjugated. Format: E20-75155-Conjugate. Price: $485 / Size: 100μl.

E20-75155-FITC$485 / 100μlE20-75155-Biotin$485 / 100μlE20-75155-HRP$485 / 100μlE20-75155-AP$485 / 100μlE20-75155-AF350$485 / 100μlE20-75155-AF405M$485 / 100μlE20-75155-AF488$485 / 100μlE20-75155-AF514$485 / 100μlE20-75155-AF532$485 / 100μlE20-75155-AF555$485 / 100μlE20-75155-AF568$485 / 100μlE20-75155-AF405S$485 / 100μlE20-75155-AF405L$485 / 100μlE20-75155-AF546$485 / 100μlE20-75155-AF594$485 / 100μlE20-75155-AF610$485 / 100μlE20-75155-AF635$485 / 100μlE20-75155-AF647$485 / 100μlE20-75155-AF680$485 / 100μlE20-75155-AF700$485 / 100μlE20-75155-AF750$485 / 100μlE20-75155-AF790$485 / 100μlE20-75155-APC$485 / 100μlE20-75155-PE$485 / 100μlE20-75155-Cy3$485 / 100μlE20-75155-Cy5$485 / 100μlE20-75155-Cy5.5$485 / 100μlE20-75155-Cy7$485 / 100μlE20-75155-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

Catalase Polyclonal Antibody | EnoGene Biotech Co. Ltd