World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
BNIP-3 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight21541DaObserved Band:22KD
Protein NameBCL2/adenovirus E1B 19 kDa protein-interacting protein 3
Human Gene Id664
Human Swiss Prot NoQ12983
Mouse Swiss Prot NoO55003
SpecificityBNIP-3 Polyclonal Antibody detects endogenous levels of BNIP-3 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameBNIP3; NIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
Functionfunction:Apoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2.,similarity:Belongs to the NIP3 family.,subcellular location:Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope.,subunit:Homodimer. Binds to BCL2. Interacts with BNIP3L. Also can interact with adenovirus E1B 19 kDa protein or Epstein-Barr virus BHRF1.,
Subcellular LocationMitochondrion. Mitochondrion outer membrane; Single-pass membrane protein. Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope. Colocalizes with ACAA2 in the mitochondria. Colocalizes with SPATA18 at the mitochondrion outer membrane.
ExpressionB-cell,Brain,Cerebellum,Kidney,Testis,,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human BNIP3. AA range:71-120
Gene NameBNIP3
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
BackgroundBCL2 interacting protein 3(BNIP3) Homo sapiens This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014],
Conjugated Antibody
This product is also available conjugated. Format: E20-75154-Conjugate. Price: $485 / Size: 100μl.
E20-75154-FITC$485 / 100μlE20-75154-Biotin$485 / 100μlE20-75154-HRP$485 / 100μlE20-75154-AP$485 / 100μlE20-75154-AF350$485 / 100μlE20-75154-AF405M$485 / 100μlE20-75154-AF488$485 / 100μlE20-75154-AF514$485 / 100μlE20-75154-AF532$485 / 100μlE20-75154-AF555$485 / 100μlE20-75154-AF568$485 / 100μlE20-75154-AF405S$485 / 100μlE20-75154-AF405L$485 / 100μlE20-75154-AF546$485 / 100μlE20-75154-AF594$485 / 100μlE20-75154-AF610$485 / 100μlE20-75154-AF635$485 / 100μlE20-75154-AF647$485 / 100μlE20-75154-AF680$485 / 100μlE20-75154-AF700$485 / 100μlE20-75154-AF750$485 / 100μlE20-75154-AF790$485 / 100μlE20-75154-APC$485 / 100μlE20-75154-PE$485 / 100μlE20-75154-Cy3$485 / 100μlE20-75154-Cy5$485 / 100μlE20-75154-Cy5.5$485 / 100μlE20-75154-Cy7$485 / 100μlE20-75154-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits