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Cell Signal Transduction Research Antibodies
IL-8 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight11098DaObserved Band:11KD
Protein NameInterleukin-8
Human Gene Id3576
Human Swiss Prot NoP10145
SpecificityIL-8 Polyclonal Antibody detects endogenous levels of IL-8 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameIL8; CXCL8; Interleukin-8; IL-8; C-X-C motif chemokine 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF;Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factor
Functionfunction:IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.,online information:Interleukin-8 entry,PTM:Several N-terminal processed forms are produced by proteolytic cleavage after secretion from at least peripheral blood monocytes, leukcocytes and endothelial cells. In general, IL-8(1-77) is referred to as interleukin-8. IL-8(6-77) is the most promiment form.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,subunit:Homodimer.,
Subcellular LocationSecreted.
ExpressionChronic myeloid leukemia cell,Kidney,Lung,Lung carcinoma,Neutrophil,Periphe,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human IL8. AA range:50-99
Gene NameIL8
DilutionIF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
BackgroundC-X-C motif chemokine ligand 8(CXCL8) Homo sapiens The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75153-Conjugate. Price: $485 / Size: 100μl.
E20-75153-FITC$485 / 100μlE20-75153-Biotin$485 / 100μlE20-75153-HRP$485 / 100μlE20-75153-AP$485 / 100μlE20-75153-AF350$485 / 100μlE20-75153-AF405M$485 / 100μlE20-75153-AF488$485 / 100μlE20-75153-AF514$485 / 100μlE20-75153-AF532$485 / 100μlE20-75153-AF555$485 / 100μlE20-75153-AF568$485 / 100μlE20-75153-AF405S$485 / 100μlE20-75153-AF405L$485 / 100μlE20-75153-AF546$485 / 100μlE20-75153-AF594$485 / 100μlE20-75153-AF610$485 / 100μlE20-75153-AF635$485 / 100μlE20-75153-AF647$485 / 100μlE20-75153-AF680$485 / 100μlE20-75153-AF700$485 / 100μlE20-75153-AF750$485 / 100μlE20-75153-AF790$485 / 100μlE20-75153-APC$485 / 100μlE20-75153-PE$485 / 100μlE20-75153-Cy3$485 / 100μlE20-75153-Cy5$485 / 100μlE20-75153-Cy5.5$485 / 100μlE20-75153-Cy7$485 / 100μlE20-75153-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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