IL-10 Polyclonal Antibody

Name: IL-10 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75138
Price: 225 USD
Availability: InStock

E20-75138Cite ID: EN0055271Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight20517DaObserved Band:20KD

Protein NameInterleukin-10

Human Gene Id3586

Human Swiss Prot NoP22301

Mouse Swiss Prot NoP18893

SpecificityIL-10 Polyclonal Antibody detects endogenous levels of IL-10 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameIL10; Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF

Functiondisease:Defects in IL10 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease.,function:Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.,online information:Interleukin-10 entry,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the IL-10 family.,subunit:Homodimer.,tissue specificity:Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.,

Subcellular LocationSecreted.

ExpressionProduced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human IL10. AA range:71-120

Gene NameIL10

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.

Backgroundinterleukin 10(IL10) Homo sapiens The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75138-Conjugate. Price: $485 / Size: 100μl.

E20-75138-FITC$485 / 100μlE20-75138-Biotin$485 / 100μlE20-75138-HRP$485 / 100μlE20-75138-AP$485 / 100μlE20-75138-AF350$485 / 100μlE20-75138-AF405M$485 / 100μlE20-75138-AF488$485 / 100μlE20-75138-AF514$485 / 100μlE20-75138-AF532$485 / 100μlE20-75138-AF555$485 / 100μlE20-75138-AF568$485 / 100μlE20-75138-AF405S$485 / 100μlE20-75138-AF405L$485 / 100μlE20-75138-AF546$485 / 100μlE20-75138-AF594$485 / 100μlE20-75138-AF610$485 / 100μlE20-75138-AF635$485 / 100μlE20-75138-AF647$485 / 100μlE20-75138-AF680$485 / 100μlE20-75138-AF700$485 / 100μlE20-75138-AF750$485 / 100μlE20-75138-AF790$485 / 100μlE20-75138-APC$485 / 100μlE20-75138-PE$485 / 100μlE20-75138-Cy3$485 / 100μlE20-75138-Cy5$485 / 100μlE20-75138-Cy5.5$485 / 100μlE20-75138-Cy7$485 / 100μlE20-75138-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.