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Cell Signal Transduction Research Antibodies
L-Selectin Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight42187DaObserved Band:42KD
Protein NameL-selectin
Human Gene Id6402
Human Swiss Prot NoP14151
Mouse Gene Id20343
Mouse Swiss Prot NoP18337
Rat Swiss Prot NoP30836
SpecificityL-Selectin Polyclonal Antibody detects endogenous levels of L-Selectin protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSELL; LNHR; LYAM1; L-selectin; CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LAM-1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; Lymph node homing receptor; TQ1; gp90-MEL; CD62L
Functionfunction:Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.,online information:L-selectin,similarity:Belongs to the selectin/LECAM family.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 2 Sushi (CCP/SCR) domains.,subunit:Interaction with PSGL1/SELPLG is required for promoting recruitment and rolling of leukocytes. This interaction is dependent on the sialyl Lewis X glycan and tyrosine sulfation modifications of PSGL1. Sulfation on Y-51 of PSGL1 is important for L-selectin binding.,tissue specificity:Expressed in B cell lines and T lymphocytes.,
Subcellular LocationCell membrane ; Single-pass type I membrane protein .
ExpressionExpressed in B-cell lines and T-lymphocytes.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from L-Selectin . at AA range: 60-140
Gene NameSELL
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Backgroundselectin L(SELL) Homo sapiens This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009],
Conjugated Antibody
This product is also available conjugated. Format: E20-75130-Conjugate. Price: $485 / Size: 100μl.
E20-75130-FITC$485 / 100μlE20-75130-Biotin$485 / 100μlE20-75130-HRP$485 / 100μlE20-75130-AP$485 / 100μlE20-75130-AF350$485 / 100μlE20-75130-AF405M$485 / 100μlE20-75130-AF488$485 / 100μlE20-75130-AF514$485 / 100μlE20-75130-AF532$485 / 100μlE20-75130-AF555$485 / 100μlE20-75130-AF568$485 / 100μlE20-75130-AF405S$485 / 100μlE20-75130-AF405L$485 / 100μlE20-75130-AF546$485 / 100μlE20-75130-AF594$485 / 100μlE20-75130-AF610$485 / 100μlE20-75130-AF635$485 / 100μlE20-75130-AF647$485 / 100μlE20-75130-AF680$485 / 100μlE20-75130-AF700$485 / 100μlE20-75130-AF750$485 / 100μlE20-75130-AF790$485 / 100μlE20-75130-APC$485 / 100μlE20-75130-PE$485 / 100μlE20-75130-Cy3$485 / 100μlE20-75130-Cy5$485 / 100μlE20-75130-Cy5.5$485 / 100μlE20-75130-Cy7$485 / 100μlE20-75130-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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