Product Information
Molecular Weight34044DaObserved Band:34KD
Protein NameLow affinity immunoglobulin gamma Fc region receptor II-b
Human Gene Id2213
Human Swiss Prot NoP31994
SpecificityCD32 Polyclonal Antibody detects endogenous levels of CD32 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
BackgroundThe Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.