CA IV Polyclonal Antibody

Name: CA IV Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75128
Price: 225 USD
Availability: InStock

E20-75128Cite ID: EN0055261Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight35032DaObserved Band:35KD

Protein NameCarbonic anhydrase 4

Human Gene Id762

Human Swiss Prot NoP22748

Mouse Swiss Prot NoQ64444

SpecificityCA IV Polyclonal Antibody detects endogenous levels of CA IV protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameCA4; Carbonic anhydrase 4; Carbonate dehydratase IV; Carbonic anhydrase IV; CA-IV

Functioncatalytic activity:H(2)CO(3) = CO(2) + H(2)O.,cofactor:Zinc.,disease:Defects in CA4 are the cause of retinitis pigmentosa type 17 (RP17) [MIM:600852]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP17 inheritance is autosomal dominant.,enzyme regulation:Inhibited by acetazolamide.,function:Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4.,similarity:Belongs to the alpha-carbonic anhydrase family.,subunit:Interacts with SLC4A4.,tissue specificity:Expressed in the endothelium of the choriocapillaris in eyes (at protein level).,

Subcellular LocationCell membrane ; Lipid-anchor, GPI-anchor .

ExpressionExpressed in the endothelium of the choriocapillaris in eyes (at protein level). Not expressed in the retinal epithelium at detectable levels.

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenSynthesized peptide derived from the Internal region of human CA IV.

Gene NameCA4

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Backgroundcarbonic anhydrase 4(CA4) Homo sapiens Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport. [provided by RefSeq, Jul 2008],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75128-Conjugate. Price: $485 / Size: 100μl.

E20-75128-FITC$485 / 100μlE20-75128-Biotin$485 / 100μlE20-75128-HRP$485 / 100μlE20-75128-AP$485 / 100μlE20-75128-AF350$485 / 100μlE20-75128-AF405M$485 / 100μlE20-75128-AF488$485 / 100μlE20-75128-AF514$485 / 100μlE20-75128-AF532$485 / 100μlE20-75128-AF555$485 / 100μlE20-75128-AF568$485 / 100μlE20-75128-AF405S$485 / 100μlE20-75128-AF405L$485 / 100μlE20-75128-AF546$485 / 100μlE20-75128-AF594$485 / 100μlE20-75128-AF610$485 / 100μlE20-75128-AF635$485 / 100μlE20-75128-AF647$485 / 100μlE20-75128-AF680$485 / 100μlE20-75128-AF700$485 / 100μlE20-75128-AF750$485 / 100μlE20-75128-AF790$485 / 100μlE20-75128-APC$485 / 100μlE20-75128-PE$485 / 100μlE20-75128-Cy3$485 / 100μlE20-75128-Cy5$485 / 100μlE20-75128-Cy5.5$485 / 100μlE20-75128-Cy7$485 / 100μlE20-75128-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.