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Cell Signal Transduction Research Antibodies
Chymase Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight27325DaObserved Band:27KD
Protein NameChymase
Human Gene Id1215
Human Swiss Prot NoP23946
Mouse Swiss Prot NoP21844
SpecificityChymase Polyclonal Antibody detects endogenous levels of Chymase protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCMA1; CYH; CYM; Chymase; Alpha-chymase; Mast cell protease I
Functioncatalytic activity:Preferential cleavage: Phe-|-Xaa > Tyr-|-Xaa > Trp-|-Xaa > Leu-|-Xaa.,function:Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Granzyme subfamily.,similarity:Contains 1 peptidase S1 domain.,subcellular location:Mast cell granules.,tissue specificity:Mast cells in lung, heart, skin and placenta.,
Subcellular LocationSecreted. Cytoplasmic granule. Mast cell granules.
ExpressionMast cells in lung, heart, skin and placenta. Expressed in both normal skin and in urticaria pigmentosa lesions.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from the Internal region of human Chymase.
Gene NameCMA1
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundchymase 1(CMA1) Homo sapiens This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015],
Conjugated Antibody
This product is also available conjugated. Format: E20-75123-Conjugate. Price: $485 / Size: 100μl.
E20-75123-FITC$485 / 100μlE20-75123-Biotin$485 / 100μlE20-75123-HRP$485 / 100μlE20-75123-AP$485 / 100μlE20-75123-AF350$485 / 100μlE20-75123-AF405M$485 / 100μlE20-75123-AF488$485 / 100μlE20-75123-AF514$485 / 100μlE20-75123-AF532$485 / 100μlE20-75123-AF555$485 / 100μlE20-75123-AF568$485 / 100μlE20-75123-AF405S$485 / 100μlE20-75123-AF405L$485 / 100μlE20-75123-AF546$485 / 100μlE20-75123-AF594$485 / 100μlE20-75123-AF610$485 / 100μlE20-75123-AF635$485 / 100μlE20-75123-AF647$485 / 100μlE20-75123-AF680$485 / 100μlE20-75123-AF700$485 / 100μlE20-75123-AF750$485 / 100μlE20-75123-AF790$485 / 100μlE20-75123-APC$485 / 100μlE20-75123-PE$485 / 100μlE20-75123-Cy3$485 / 100μlE20-75123-Cy5$485 / 100μlE20-75123-Cy5.5$485 / 100μlE20-75123-Cy7$485 / 100μlE20-75123-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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