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Cell Signal Transduction Research Antibodies
SCP-3 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight27729DaObserved Band:27KD
Protein NameSynaptonemal complex protein 3
Human Gene Id50511
Human Swiss Prot NoQ8IZU3
Mouse Gene Id20962
Mouse Swiss Prot NoP70281
SpecificitySCP-3 Polyclonal Antibody detects endogenous levels of SCP-3 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSYCP3; SCP3; Synaptonemal complex protein 3; SCP-3
Functiondisease:Defects in SYCP3 are associated with azoospermia due to perturbations of meiosis [MIM:270960].,function:Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development.,similarity:Belongs to the XLR/SYCP3 family.,subcellular location:In tripartite segments of synaptonemal complexes, irrespective of whether these are synapsed or unsynapsed.,subunit:Interacts with SYCP2.,tissue specificity:Testis-specific.,
Subcellular LocationNucleus . Chromosome . Chromosome, centromere . It is present in early unpaired cores, in the lateral domains of the synaptonemal complex and in the chromosome cores when they separate at diplotene. It is found axial to the metaphase I chromosomes and in association with pairs of sister centromeres. The centromere-associated protein becomes dissociated from the centromeres at anaphase II and is not found in mitotic metaphase centromeres. .
ExpressionTestis-specific.,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from the Internal region of human SCP-3.
Gene NameSYCP3
DilutionWB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Backgroundsynaptonemal complex protein 3(SYCP3) Homo sapiens This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010],
Conjugated Antibody
This product is also available conjugated. Format: E20-75117-Conjugate. Price: $485 / Size: 100μl.
E20-75117-FITC$485 / 100μlE20-75117-Biotin$485 / 100μlE20-75117-HRP$485 / 100μlE20-75117-AP$485 / 100μlE20-75117-AF350$485 / 100μlE20-75117-AF405M$485 / 100μlE20-75117-AF488$485 / 100μlE20-75117-AF514$485 / 100μlE20-75117-AF532$485 / 100μlE20-75117-AF555$485 / 100μlE20-75117-AF568$485 / 100μlE20-75117-AF405S$485 / 100μlE20-75117-AF405L$485 / 100μlE20-75117-AF546$485 / 100μlE20-75117-AF594$485 / 100μlE20-75117-AF610$485 / 100μlE20-75117-AF635$485 / 100μlE20-75117-AF647$485 / 100μlE20-75117-AF680$485 / 100μlE20-75117-AF700$485 / 100μlE20-75117-AF750$485 / 100μlE20-75117-AF790$485 / 100μlE20-75117-APC$485 / 100μlE20-75117-PE$485 / 100μlE20-75117-Cy3$485 / 100μlE20-75117-Cy5$485 / 100μlE20-75117-Cy5.5$485 / 100μlE20-75117-Cy7$485 / 100μlE20-75117-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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