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Cell Signal Transduction Research Antibodies
JAM-B Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight33207DaObserved Band:33KD
Protein NameJunctional adhesion molecule B
Human Gene Id58494
Human Swiss Prot NoP57087
Mouse Gene Id67374
Mouse Swiss Prot NoQ9JI59
SpecificityJAM-B Polyclonal Antibody detects endogenous levels of JAM-B protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameJAM2; C21orf43; VEJAM; Junctional adhesion molecule B; JAM-B; Junctional adhesion molecule 2; JAM-2; Vascular endothelial junction-associated molecule; VE-JAM; CD322
Functionfunction:May play a role in the processes of lymphocyte homing to secondary lymphoid organs.,similarity:Belongs to the immunoglobulin superfamily.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subcellular location:Localized at tight junctions of both epithelial and endothelial cells.,subunit:Interacts with JAM3.,tissue specificity:Highest expression in the heart, placenta, lung, foreskin and lymph node. Prominently expressed on high endothelial venules, also present on the endothelia of other vessels. Localized to the intercellular boundaries of high endothelial cells.,
Subcellular LocationCell membrane ; Single-pass type I membrane protein . Cell junction . Cell junction, tight junction . Localized at tight junctions of both epithelial and endothelial cells (By similarity). Specifically localized within the somatodendritic compartment of neurons and excluded from the axon (By similarity). .
ExpressionHighly expressed in heart, placenta, lung, foreskin and lymph node (PubMed:10779521, PubMed:10945976). Prominently expressed on high endothelial venules and also present on the endothelia of other vessels (at protein level) (PubMed:10779521, PubMed:10945976). Also expressed in the brain in the caudate nuclei (PubMed:31851307).,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from the Internal region of human JAM-B.
Gene NameJAM2
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Backgroundjunctional adhesion molecule 2(JAM2) Homo sapiens This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012],
Conjugated Antibody
This product is also available conjugated. Format: E20-75115-Conjugate. Price: $485 / Size: 100μl.
E20-75115-FITC$485 / 100μlE20-75115-Biotin$485 / 100μlE20-75115-HRP$485 / 100μlE20-75115-AP$485 / 100μlE20-75115-AF350$485 / 100μlE20-75115-AF405M$485 / 100μlE20-75115-AF488$485 / 100μlE20-75115-AF514$485 / 100μlE20-75115-AF532$485 / 100μlE20-75115-AF555$485 / 100μlE20-75115-AF568$485 / 100μlE20-75115-AF405S$485 / 100μlE20-75115-AF405L$485 / 100μlE20-75115-AF546$485 / 100μlE20-75115-AF594$485 / 100μlE20-75115-AF610$485 / 100μlE20-75115-AF635$485 / 100μlE20-75115-AF647$485 / 100μlE20-75115-AF680$485 / 100μlE20-75115-AF700$485 / 100μlE20-75115-AF750$485 / 100μlE20-75115-AF790$485 / 100μlE20-75115-APC$485 / 100μlE20-75115-PE$485 / 100μlE20-75115-Cy3$485 / 100μlE20-75115-Cy5$485 / 100μlE20-75115-Cy5.5$485 / 100μlE20-75115-Cy7$485 / 100μlE20-75115-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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