Fractalkine Receptor Polyclonal Antibody

Name: Fractalkine Receptor Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75112
Price: 225 USD
Availability: InStock

E20-75112Cite ID: EN0055245Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight40396DaObserved Band:40KD

Protein NameCX3C chemokine receptor 1

Human Gene Id1524

Human Swiss Prot NoP49238

Mouse Gene Id13051

Mouse Swiss Prot NoQ9Z0D9

Rat Gene Id171056

Rat Swiss Prot NoP35411

SpecificityFractalkine Receptor Polyclonal Antibody detects endogenous levels of Fractalkine Receptor protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameCX3CR1; CMKBRL1; GPR13; CX3C chemokine receptor 1; C-X3-C CKR-1; CX3CR1; Beta chemokine receptor-like 1; CMK-BRL-1; CMK-BRL1; Fractalkine receptor; G-protein coupled receptor 13; V28

Functionfunction:Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1.,polymorphism:Variations in CX3CR1 are associated with rapid progression to AIDS [MIM:609423]. Increased susceptibility to HIV infection and rapid progression to AIDS are associated with the Ile-249/Met-280 haplotype.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts with human respiratory syncytial virus (HRSV) protein G; this interaction modulates host immune response. Interacts with HIV-1 envelope polyprotein gp160.,tissue specificity:Expressed in lymphoid and neural tissues.,

Subcellular LocationCell membrane ; Multi-pass membrane protein .

ExpressionExpressed in lymphoid and neural tissues (PubMed:7590284). Expressed in lymphocyte subsets, such as natural killer (NK) cells, gamma-delta T-cells and terminally differentiated CD8(+) T-cells (PubMed:12055230). Expressed in smooth muscle cells in atherosclerotic plaques (PubMed:14581400).,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenSynthesized peptide derived from Fractalkine Receptor . at AA range: 120-200

Gene NameCX3CR1

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

BackgroundC-X3-C motif chemokine receptor 1(CX3CR1) Homo sapiens Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75112-Conjugate. Price: $485 / Size: 100μl.

E20-75112-FITC$485 / 100μlE20-75112-Biotin$485 / 100μlE20-75112-HRP$485 / 100μlE20-75112-AP$485 / 100μlE20-75112-AF350$485 / 100μlE20-75112-AF405M$485 / 100μlE20-75112-AF488$485 / 100μlE20-75112-AF514$485 / 100μlE20-75112-AF532$485 / 100μlE20-75112-AF555$485 / 100μlE20-75112-AF568$485 / 100μlE20-75112-AF405S$485 / 100μlE20-75112-AF405L$485 / 100μlE20-75112-AF546$485 / 100μlE20-75112-AF594$485 / 100μlE20-75112-AF610$485 / 100μlE20-75112-AF635$485 / 100μlE20-75112-AF647$485 / 100μlE20-75112-AF680$485 / 100μlE20-75112-AF700$485 / 100μlE20-75112-AF750$485 / 100μlE20-75112-AF790$485 / 100μlE20-75112-APC$485 / 100μlE20-75112-PE$485 / 100μlE20-75112-Cy3$485 / 100μlE20-75112-Cy5$485 / 100μlE20-75112-Cy5.5$485 / 100μlE20-75112-Cy7$485 / 100μlE20-75112-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.