Product Information
Molecular Weight88309DaObserved Band:88KD
Protein NameCadherin-6
Human Gene Id1004
Human Swiss Prot NoP55285
Mouse Gene Id12563
Mouse Swiss Prot NoP97326
Rat Gene Id25409
Rat Swiss Prot NoP55280
SpecificityK-cadherin Polyclonal Antibody detects endogenous levels of K-cadherin protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCDH6; Cadherin-6; Kidney cadherin; K-cadherin
Functionfunction:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,tissue specificity:Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.,
Subcellular LocationCell membrane; Single-pass type I membrane protein.
ExpressionHighly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.,
Backgroundcadherin 6(CDH6) Homo sapiens This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011],