Product Information
Molecular Weight54816DaObserved Band:54KD
Protein NameDNA-directed DNA/RNA polymerase mu
Human Gene Id27434
Human Swiss Prot NoQ9NP87
Mouse Swiss Prot NoQ9JIW4
SpecificityDNA Pol μ Polyclonal Antibody detects endogenous levels of DNA Pol μ protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NamePOLM; polmu; DNA-directed DNA/RNA polymerase mu; Pol Mu; Terminal transferase
Functioncatalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Magnesium.,function:Seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.,similarity:Belongs to the DNA polymerase type-X family.,similarity:Contains 1 BRCT domain.,tissue specificity:Expressed in a number of tissues. Abundant in thymus.,
Subcellular LocationNucleus .
ExpressionExpressed in a number of tissues. Abundant in thymus.,
Backgroundcatalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Magnesium.,function:Seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.,similarity:Belongs to the DNA polymerase type-X family.,similarity:Contains 1 BRCT domain.,tissue specificity:Expressed in a number of tissues. Abundant in thymus.,